Early ultrasound for diagnosis and treatment of vascular adverse events with hyaluronic acid fillers

Schelke, Leonie; Velthuis, Peter; Kadouch, Jonathan; Swift, Arthur

doi:10.1016/j.jaad.2019.07.032

Cited by 57 publications

(46 citation statements)

References 48 publications

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“…Details on a number of these cases were published earlier. 5 CaHA = calcium hydroxyapatite filler; DUS = doppler ultrasound; HA = hyaluronic acid filler.…”

Section: Resultsmentioning

confidence: 99%

“…Our treatment for hyaluronic acid filler obstruction is given elsewhere. 5 In calcium hydroxyapatite-related vascular blockages, sodium-thiosulphate injections (250 mg/mL-0.2 mL per cm 2 ) were utilized. 8 All patients provided written consent for the treatment procedure.…”

Section: Methodsmentioning

confidence: 99%

“…There are no barriers for patients to visit, because the city of Rotterdam can be reached by train in a maximum of 3.5 hours from every part of the Netherlands. Most physicians in cosmetic medicine in the Netherlands are aware of the problem of vascular occlusion and our competencies, because we have published several papers on filler complications in Dutch as in international journals 5 , 6 and in the lay press. In the complications debate of the Dutch Society for Cosmetic Medicine, our group has been actively engaged since its foundation.…”

mentioning

confidence: 99%

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Incidence of Vascular Obstruction After Filler Injections

Schelke¹,

Decates²,

Kadouch³

et al. 2020

Aesthetic Surgery Journal

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“…Details on a number of these cases were published earlier. 5 CaHA = calcium hydroxyapatite filler; DUS = doppler ultrasound; HA = hyaluronic acid filler.…”

Section: Resultsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Incidence of Vascular Obstruction After Filler Injections

Schelke¹,

Decates²,

Kadouch³

et al. 2020

Aesthetic Surgery Journal

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“…Hyaluronic acid is degraded into small molecules of hyaluronic acid by enzymes, which might cause allergies (Signorini et al 2016). On the other hand, due to the high molecular weight of hyaluronic acid, there are certain difficulties in the application of the formulation (Schelke et al 2019). Therefore, people are gradually focussing on finding alternatives from natural plants.…”

Section: Skin-moisturizing Effectmentioning

confidence: 99%

Current advances of Dendrobium officinale polysaccharides in dermatology: a literature review

Guo

et al. 2020

Pharmaceutical Biology

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Context: Dendrobium officinale Kimura et Migo (Orchidaceae) is a naturally occurring precious traditional Chinese medicine (TCM) originally used in treating yin-deficiency diseases. The main active substances of Dendrobium officinale are polysaccharides (DOP). Recent findings highlighted the potential of DOP as a promising natural material for medical use with a diversity of pharmaceutical effects. Objective: In this review, we provide a systematic discussion of the current development and potential pharmacological effects of Dendrobium officinale polysaccharides in dermatology. Methods: English and Chinese literature from 1987 to 2019 indexed in databases including PubMed, PubMed Central, Web of Science, ISI, Scopus and CNKI (Chinese) was used. Dendrobium officinale, Dendrobium officinale polysaccharides, phytochemistry, chemical constituents, biological activities, and pharmacological activities were used as the key words. Results: Dendrobium officinale polysaccharides have been found to possess hair growth promoting, skin moisturising and antioxidant effects, which are highly valued by doctors and cosmetic engineers. We highlighted advances in moisturising and antioxidant properties from in vivo and in vitro studies. Dendrobium officinale polysaccharides exhibited strong antioxidant effects by decreasing free radicals, enhancing antioxidant system, inhibiting nuclear factor-kappa B and down-regulating inflammatory response. Conclusions: Our review is a foundation to inspire further research to facilitate the application of Dendrobium officinale polysaccharides in dermatology and promote active research of the use of TCM in dermatology.

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“…An additional item in this regard is the use of duplex ultrasound to improve filler safety. 4,5 The application of (duplex) ultrasound in cosmetic dermatology In Figure 1A, we present one of our cases with occlusion of the superior labial artery who was managed at our filler complication clinic…”

Section: Dear Editormentioning

confidence: 99%