Early weight loss in adolescents following bariatric surgery predicts weight loss at 12 and 24 months

Abstract

Summary Background Growing evidence supports the efficacy of paediatric bariatric surgery. However, there is a paucity of data examining adolescent outcomes post surgery. Among adults, studies have shown that early weight loss is associated with long‐term weight loss. Therefore, the aim of our study was to investigate the association between early weight loss at 3 months with longer‐term weight loss at 12 and 24 months in adolescents post surgery. We hypothesized that patients who have greater weight loss within the first 3 months will have greater weight loss at 12 and 24 months post surgery. Methods A retrospective chart review of bariatric surgery patients (n = 28) was conducted. Anthropometric measurements at baseline and 3, 12, and 24 months were analysed. Results Percent of excess weight loss (%EWL) at 3, 12, and 24 months were 33.6 ± 11.3%, 55.0 ± 20.5%, and 55.1 ± 27.1%, respectively. %EWL at 3 months was positively associated with %EWL at 12 and 24 months (P < 0.05). Receiver operating characteristic curve results identified a cut‐off of greater than or equal to 30%EWL at 3 months predicted successful weight loss, defined as greater than or equal to 50%EWL at 12 and 24 months. Conclusion These findings demonstrate that majority of weight loss among adolescents occurs within the first postoperative year. Greater %EWL by 3 months post surgery predicts successful and sustained weight loss over time.

Body Adiposity Index Is Predictive of Weight Loss after Roux-en-Y Gastric Bypass

“…Indexes of body fatness and risk factors of metabolic disorders are commonly used in clinical practices. Due to the significant variability among obese subjects [4], it is important to identify a prognostic marker of metabolic This model was stratified according to median of %EWL, adjusted for age and T2D state. OR, odds ratio; CI, confidence interval; %EWL, percent excess weight loss.…”

“…A study with longer follow-up time remains unaccomplished. However, it has been proved that most of the patients experienced maximum weight change up to 12 months [4]. Additional studies with longer follow-up period are necessary to better clarify whether these adiposity indexes could predict long-term benefits after bariatric surgeries.…”

“…Obesity is a worldwide chronic disease that triggers metabolic disturbances including type 2 diabetes mellitus (T2DM), dyslipidemia, and cardiovascular diseases [1,2]. Of note, bariatric surgery is the most common and effective treatment for severe obesity [3], which not only induces considerable weight loss but also improves obesityrelated comorbidities as well [4]. As the most commonly used bariatric surgery type, Roux-en-Y gastric bypass (RYGB) can result in greater percent of excess body mass index loss (%EBMIL) in morbidly obese patients compared with other surgery types [1,2].…”

Update on pediatric metabolic and bariatric surgery

“…Numerous contemporary reports support the role of metabolic and bariatric surgery in the pediatric population as a safe and effective treatment option for severe obesity; with current estimates of approximately 1600 cases per year in the United States. 4,5,[12][13][14][15][16]29,30,32,35,57,[61][62][63][64] As shown in Table 1, the current clinical eligibility criteria for metabolic and bariatric surgery in the pediatric age group continues to evolve since being initially introduced in the early 2000s, 65 with current recommendation for use among individuals with either class 2 obesity (BMI ≥120% of the 95th percentile) plus a significant comorbid condition, including but not limited to disorders such as severe OSA, T2DM, hypertension or NASH, or class 3 obesity (BMI ≥140% of the 95th percentile) regardless of the status of concurrent obesity-related illnesses.…”

Adiposity, psychomotor and behaviour outcomes of children born after maternal bariatric surgery

“…In order to counsel our patients in a correct way, we urgently need data on the long‐term effects of the surgery techniques that are currently used 18 . In this study, we prospectively studied growth and development of the offspring of mothers who underwent bariatric surgery before pregnancy and compared them to the offspring of controls with a comparable pre‐pregnancy BMI and normal weight controls.…”