Early whooping cough immunization

CHEMICAL STUDIES ON CELLULAR COMPONENTS OFBORDETELLA PERTUSSISI

“…They also demonstrated that the agglutinogen produced an allergic-type skin reaction in sensitized animals and human beings. Because of the practical need of a simple and specific method to test susceptibility to whooping cough and to ascertain the effect of vaccination against whooping cough, clinical use of the agglutinogen as a skin test reagent has been reported by many authors (Felton and Flosdorf, 1943;Flosdorf et al, 1943;Sauer and Markley, 1946;Felton and Flosdorf, 1946;Felton, Smolens, and Mudd, 1946;Halpern and Halpern, 1948;Miller, Ryan, and Havard, 1948;Kohn et al, 1950;Zenyoji, 1952;Someya, 1955).…”

19. Individual life cycles and family cycles. A comparison of perspectives

“…In these cases ages of household heads range from 18 to 40, heading households of 4 and 18 members respectively.) 18 The proportionate number of household heads which grows until it reaches its peak in the 40-49 age group in Orasac, 1863, with a negligible number of women. Considering the male population, the proportions for the different age groups declines progressively after remaining relatively stable for the 10-19 and 20-29 age groups (20.7 % and 18 % respectively), reaching 10.2 % for the 30-39 group and leveling off to 5.7% for the 40-49 and 50-59 groups.…”

I. Immunological and Other Biological Activities of Bordetella Pertussis Antigens

“…Agglutinogen has been used as a skin-test antigen to detect susceptibility to whooping cough in children (29,30,31,37,91), to evaluate the efficacy of vaccines (29,30,37,46,65,87,91), and to determine the extent of protection induced by vaccines (31, 65). Flosdorf et al (37) found that skin test in children acted as a booster and increased agglutinin titers in the blood; they reported that 99% of children from 6 to 14 months of age who had no history of exposure to whooping cough had negative skin tests, whereas 75cc0 of those with a history of whooping cough had positive skin tests.…”