Triboelectric nanogenerators (TENGs) stand at the forefront of energy harvesting innovation, transforming mechanical energy into electrical power through triboelectrification and electrostatic induction. This groundbreaking technology addresses the urgent need for sustainable and renewable energy solutions, opening new avenues for self-powered systems. Despite their potential, TENGs face challenges such as material optimization for enhanced triboelectric effects, scalability, and improving conversion efficiency under varied conditions. Durability and environmental stability also pose significant hurdles, necessitating further research towards more resilient systems. Nature inspired TENG designs offer promising solutions by emulating biological processes and structures, such as the energy mechanisms of plants and the textured surfaces of animal skins. This biomimetic approach has led to notable improvements in material properties, structural designs, and overall TENG performance, including enhanced energy conversion efficiency and environmental robustness. The exploration into bio-inspired TENGs has unlocked new possibilities in energy harvesting, self-powered sensing, and wearable electronics, emphasizing reduced energy consumption and increased efficiency through innovative design. This review encapsulates the challenges and advancements in nature inspired TENGs, highlighting the integration of biomimetic principles to overcome current limitations. By focusing on augmented electrical properties, biodegradability, and self-healing capabilities, nature inspired TENGs pave the way for more sustainable and versatile energy solutions.