Enabling scientists to use remote distributed infrastructures, parametrize and execute common science-domain applications transparently is actual and a highly relevant field of distributed computing. For this purpose a general solution is the concept of Science Gateways. WS-PGRADE/gUSE system offers a transparent and web-based interface to access distributed resources (grids, clusters or clouds), extended by a powerful generic purpose workflow editor and enactment system, which can be used to compose scientific applications into data-flow based workflow structures. It's a generic web-based portal solution to organize scientific applications in a workflow structure and execute them on remote computational resources. As the portal defines nodes as blackbox applications uploaded by the users, it does not provide any application specific interface by default. In this paper we show what kind of tools, APIs and interfaces are available in WS-PGRADE/gUSE to customize it to have an application specific gateway.