easyPET: a novel concept for an affordable tomographic system

Arosio, V.; Caccia, M.; Castro, I.F.; Correia, P.M.M.; Mattone, C.; Moutinho, L.M.; Santoro, R.; Silva, Ana Luísa; Veloso, J.F.C.A.

doi:10.1016/j.nima.2016.05.004

Cited by 5 publications

(4 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The board rotates around the center, where the mouse is positioned, covering the same field of view as the conventional micro-PET systems. The easyPET.3D distinguishes itself from the other systems by its performance, cost and simplicity [9]. In Figure 1 is presented the easyPET.3D imaging system, as well as its user interface and mouse bed.…”

Section: Imaging System-easypet3dmentioning

confidence: 99%

Development of a New Integrated System for Vital Sign Monitoring in Small Animals

Oliveira

Correia

Silva

et al. 2022

Sensors

View full text Add to dashboard Cite

Monitoring the vital signs of mice is an essential practice during imaging procedures to avoid populational losses and improve image quality. For this purpose, a system based on a set of devices (piezoelectric sensor, optical module and thermistor) able to detect the heart rate, respiratory rate, body temperature and arterial blood oxygen saturation (SpO2) in mice anesthetized with sevoflurane was implemented. Results were validated by comparison with the reported literature on similar anesthetics. A new non-invasive electrocardiogram (ECG) module was developed, and its first results reflect the viability of its integration in the system. The sensors were strategically positioned on mice, and the signals were acquired through a custom-made printed circuit board during imaging procedures with a micro-PET (Positron Emission Tomography). For sevoflurane concentration of 1.5%, the average values obtained were: 388 bpm (beats/minute), 124 rpm (respirations/minute) and 88.9% for the heart rate, respiratory rate and SpO2, respectively. From the ECG information, the value obtained for the heart rate was around 352 bpm for injectable anesthesia. The results compare favorably to the ones established in the literature, proving the reliability of the proposed system. The ECG measurements show its potential for mice heart monitoring during imaging acquisitions and thus for integration into the developed system.

show abstract

Section: Imaging System-easypet3dmentioning

confidence: 99%

Development of a New Integrated System for Vital Sign Monitoring in Small Animals

Oliveira

Correia

Silva

et al. 2022

Sensors

View full text Add to dashboard Cite

show abstract

“…Each time a coincidence is detected between the two scintillation detectors, the line-of-response (LOR) considered for the two annihilation photons trajectory is the line between the two front faces of the scintillation detectors. In this configurations, the parallax effect is avoided [5,4]. The reason is that photons always penetrate the scintillation detectors perpendicularly to the front face, avoiding the uncertainty in the LOR determination.…”

Section: Introductionmentioning

confidence: 99%

“…Included in this exotic geometries of PET scanners is the EasyPET system developed at the University of Aveiro. This PET system is based in an innovative method in which two detecting cells rotate according two axes, performing a full 2D scan [4,5] similar to the one obtained with a ring based PET scanner.A scheme of the EasyPET working system is depicted in figure 1 and figure 2. The acquistion method was patented by the University of Aveiro [6] and the technology was licensed to CAEN S.p.A., being now a commercial product, part of the CAEN educational catalog [7].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

An EDUGATE simulation toolkit based on the educational easyPET

Correia¹,

Menoita²,

Silva³

et al. 2019

Biomed. Phys. Eng. Express

View full text Add to dashboard Cite

EasyPET is a new concept of a Positron Emission Tomography (PET) scanner using an innovative acquisition method based on two rotation axes for the movement of detector pairs. Due to its simplicity, it is suitable for education purposes, to teach students about the PET technology and its basic concepts, from the radiation detecting and analogue pulse analysis to the coincidence sorting and image reconstruction. The concept allows achieving high and uniform position resolution over the whole field of view (FoV), by eliminating parallax errors due to the depth of interaction (DoI), which are typical of ring-based PET systems, so quality images are obtained even without state-of-the-art image reconstruction algorithms. The technology developed at the University of Aveiro with a patent-pending, is licensed to CAEN S.p.A, and included in the educational catalogue of the company. In this work, a simulation toolkit based in the Edugate platform was developed to simulate the EasyPET system. It can simulate all the physical aspects of the product, such us the scanning range, variable Field-of-View (FOV), scintillator energy resolution, coincidence time and energy window, among others. A simple image reconstruction algorithm based on Filtered-back-projection (FBP) is implemented. The toolkit allows a quick analysis in classroom of the simulation results. The platform was also used to study the new EasyPET 3D version, and a simulation of a NEMA NU 4-2008 IQ phantom was performed, demonstrating the capability of the platform not only for education purposes but also for research.Patent Universidade de Aveiro: PCT/IB2016/051487

show abstract