EAU Guidelines on Prostate Cancer

Aus, G.; Abbou, Clément‐Claude; Bolla, M.; Heidenreich, Axel; Schmid, Hans Peter; Poppel, Hendrik Van; Wolff, J. M.; Zattoni, F.

doi:10.1016/j.eururo.2005.06.001

Cited by 500 publications

(269 citation statements)

References 10 publications

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“…4,7,28,29 Men with pT3 disease in whom lymphadenectomy was not performed, as the chance of lymph node metastases was o5%, 30 were included. Patients were categorised as having a poor outcome (relapse group) if they developed biochemical recurrence within 2 years of surgery, defined as a serum PSA level of greater than 0.2 31,32 or 0.5 ng/ ml 33 if a less sensitive assay had been used. Men with a good outcome (non-relapse group), whose serum PSA level remained undetectable for at least 3 years after RP, were extracted for comparison.…”

Section: Methodsmentioning

confidence: 99%

Allelic imbalance and biochemical outcome after radical prostatectomy

Bott

Masters

Parkinson

et al. 2006

Prostate Cancer Prostatic Dis

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Objective: To compare the incidence of allelic imbalance (AI) in men with rapid disease progression with those who remained disease free after radical prostatectomy, with the aim of identifying genetic markers to predict prognosis and guide further treatment. Patients and methods: Tumour and normal DNA were extracted from two matched groups of 31 men with extracapsular node-negative (pT3N0) prostate cancer who had undergone radical prostatectomy. One group comprised men who developed biochemical recurrence within 2 years of surgery and one group were prostate-specific antigen (PSA) free for at least 3 years. Men were matched for Gleason grade, preoperative PSA and pathological stage. Analysis was performed by genotyping. Results: Allelic imbalance was analysed using 30 markers, and was seen in at least one marker in 57 (92%) of the cases. Deletion at marker D10S211 (10p12.1) was significantly more common in the relapse group than the non-relapse group (35 vs 5%, P ¼ 0.03). Conclusions: This study demonstrates significant association between AI on chromosome 10 and biochemical progression after radical prostatectomy.

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Section: Methodsmentioning

confidence: 99%

Allelic imbalance and biochemical outcome after radical prostatectomy

Bott

Masters

Parkinson

et al. 2006

Prostate Cancer Prostatic Dis

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“…In intermediate and high-risk prostate cancer, PLND is a prerequisite to determining accurate staging, predicting prognosis, and deciding on therapeutic treatment [3,4].…”

Section: Discussionmentioning

confidence: 99%

“…Physical examination revealed right thigh swelling, heating sense, and tenderness. On laboratory examination, his white blood cell count was 19,700×10 3 /l (neutrophils, 89%), erythrocyte sedimentation rate was 69 mg/h, and C-reactive protein level was 217.4 mg/L. Urine analysis was unremarkable.…”

Section: Case Reportmentioning

confidence: 99%

Infected Lymphocele Extending to the Leg after Robot-Assisted Radical Prostatectomy and Pelvic Lymph Node Dissection

Jung

2017

Urogenit Tract Infect

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Lymphocele infection is a rare complication after radical prostatectomy and pelvic lymph node dissection (PLND). Here, we present a case of lymphocele infection that extended to the leg two months after robot-assisted laparoscopic radical prostatectomy and PLND. The patient was a 60-year-old man whose chief complaints were fever, chills, and right thigh pain. Computed tomography showed infected lymphocele with right thigh abscess. After percutaneous drainage and intravenous antibiotics, the infection and right thigh abscess were resolved. Keywords Case ReportA lymphocele is a collection of lymphatic fluid within the body that is not bordered by epithelial lining; this occurs as a consequence of surgical dissection of afferent lymphatic vessels. After radical prostatectomy and pelvic lymph node dissection (PLND), incidence of symptomatic lymphocele is rare; however, asymptomatic lymphocele occurs in up to 61% of cases [1]. Symptomatic lymphoceles present infection, deep vein thrombosis (DVT), pulmonary embolism, and/or leg edema, with infection being the most common concurrent presentation [2].Here, we present a case of infected lymphocele that extended to the leg after robot-assisted radical prostatectomy (RARP) and PLND. CASE REPORTA 60-year-old man referred to our hospital presented fever, chills, myalgia, and right thigh pain. He underwent RARP and PLND at a different hospital two months prior to his referral. He experienced myalgia and right thigh pain for four days and took amoxicillin for two days. However, fever and right thigh pain persisted, causing him to visit our emergency department. His blood pressure was 130/80 mmHg, body temperature was 37.5 o C, pulse rate was 110 beats/minute, and respiratory rate was 26 breaths/minute. Physical examination revealed right thigh swelling, heating sense, and tenderness. On laboratory examination, his white blood cell count was 19,700×10 3 /l (neutrophils, 89%), erythrocyte sedimentation rate was 69 mg/h, and C-reactive protein level was 217.4 mg/L. Urine analysis was unremarkable. Abdominopelvic computed tomography (CT) scan showed a cystic mass measuring 8.5×5.4 cm with a thick capsule in the right pelvic cavity, and another cystic mass measuring 8.3×4.6 cm with heterogeneous enhancement in the right thigh (Fig. 1). He underwent percutaneous drainage of the right infected lymphocele and was administered with intravenous antibiotics. Right thigh abscess decreased in size after percutaneous drainage (Fig. 2); pus culture revealed Staphylococcus aureus. Ten days after puncture, the lymphocele

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“…W tej skali wyróżnia się 3 stopnie złośliwości: niski (2-4), średni (5-7) oraz wysoki (8)(9)(10). Im wyższy stopień, tym większe ryzyko progresji choroby i przerzutów, a także więk-sze prawdopodobieństwo krótszego czasu przeży-cia [4].…”

Section: Rak Gruczołu Krokowegounclassified