EBUS-TBNA for the Clarification of PET Positive Intra-Thoracic Lymph Nodes—an International Multi-Centre Experience

Rintoul, Robert C.; Tournoy, Kurt G.; Daly, Hesham El; Carroll, Nicholas; Buttery, Robert; Kralingen, Klaas van; Meerbeeck, Jan P. van; Rabe, Klaus F.; Annema, Jouke T.

doi:10.1097/jto.0b013e3181914357

Cited by 92 publications

(55 citation statements)

References 23 publications

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“…44,45 Thoracentesis with cytologic analysis is recommended if a pleural effusion is large enough to be safely accessed via ultrasound guidance. If thoracentesis does not show malignant cells, then thoracoscopy can be considered to document pleural involvement, which would indicate extensive-stage disease.…”

Section: Stagingmentioning

confidence: 99%

Small Cell Lung Cancer

Kalemkerian¹,

Akerley²,

Bogner³

et al. 2011

J Natl Compr Canc Netw

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Section: Stagingmentioning

confidence: 99%

Small Cell Lung Cancer

Kalemkerian¹,

Akerley²,

Bogner³

et al. 2011

J Natl Compr Canc Netw

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“…51,[60][61][62][63][64][65][66] In patients whose PET scans were suspected of showing nodal metastases, EBUS had sensitivities between 90% and 95% and negative predictive values between 60% and 97%. 52,67,68 In a study in 100 patients with NSCLC without nodal enlargement at CT, sensitivity and negative predictive value were 92% and 96%, respectively. 69 In another series of 100 patients with NSCLC with small (mean diameter, 7.9 mm) and PET-negative nodes, EBUS detected mediastinal malignancy in 9% of patients and had a sensitivity and a negative predictive value of 89% and 99%, respectively.…”

Section: Nodal Staging By Ebusmentioning

confidence: 98%

EUS and EBUS in Non–Small Cell Lung Cancer

Crombag

Annema

2011

Endosonography

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“…Thus invasive mediastinal staging either by endobronchial ultrasoundguided fine needle aspiration or by mediastinoscopy should be routinely performed [21]. An ongoing discussion exists about the classificiation of ipsilateral supraclavicular nodes and whether the classification as N3 is accurate in the view of the proximity to the primary tumor [7,22].…”

Section: Clinical Presentation and Diagnostic Assessmentmentioning

confidence: 99%

Current treatment concepts of Pancoast tumors

Aigner

Klepetko

2010

Eur Surg

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Zusammenfassung. Grundlagen: Nicht-kleinzellige Bronchuskarzinome, welche die obere Thoraxapertur infiltrieren -auch Pancoast-Tumore genannt -sind aufgrund ihrer Nahebeziehung zu den vitalen Strukturen des Apex ein therapeutisch besonders herausfordernder Teil der Lungenkarzinome.Methodik: Diese Reviewarbeit fokussiert auf klinische Ergebnisse unterschiedlicher Therapieansätze und auf verschiedene chirurgische Zugänge zu Pancoast-Tumoren.Ergebnisse: Die Therapiekonzepte haben sich im Laufe der Zeit substantiell weiterentwickelt, was in signifikant erhöhte Langzeitü berlebensraten resultiert.Schlussfolgerungen: Ein multimodaler Zugang mit einer neoadjuvanten Chemoradiatio gefolgt von chirurgischer Resektion hat sich als Standardtherapie bei lokalisiertem Krankheitsgeschehen etabliert.Schlüsselwörter: Tumore der Thoraxapertur, PancoastTumor, Lungenkrebs, NSCLC, multimodale Behandlung.Summary. Background: Non-small-cell lung cancers involving the superior sulcus, also termed Pancoast tumors, are a challenging subset of lung carcinomas due to their proximity to vital structures at the thoracic inlet.Methods: This review focuses on clinical outcome data of different treatment regimens and surgical approaches to Pancoast tumors.Results: Therapeutical standards have constantly evolved over time leading to significantly improved long-term survival rates.Conclusions: A multimodal regimen approach consisting of induction chemoradiation followed by surgical resection has become the standard treatment concept in localized disease.

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EBUS-TBNA for the Clarification of PET Positive Intra-Thoracic Lymph Nodes—an International Multi-Centre Experience

Abstract: EBUS-TBNA offers an effective accurate, minimally invasive strategy for evaluating FDG avid hilar and mediastinal lymph nodes. However, negative findings should be confirmed by surgical staging.

Cited by 92 publications

References 23 publications

Small Cell Lung Cancer

Small Cell Lung Cancer

EUS and EBUS in Non–Small Cell Lung Cancer

Current treatment concepts of Pancoast tumors

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