EBV epiglottitis: Primary supraglottic viral infection in a pediatric immunocompetent host

Supraglottitis, a new paradigm in acute inflammation of pediatric airway

“…This patient had a clinical presentation similar to the other patients from the series, which could be related to this patient's virus coinfection. Despite virus being more frequent in other upperway pathologies such as acute laryngitis, there have been reported cases of supraglottitis caused by Epstein − Barr Virus and parainfluenza A and, in half of our cases, the only isolated etiological agent in half of them was a virus 3 . Isolated pathogens from nasopharyngeal samples cannot confirm etiology due to the non‐sterile zone; nevertheless, this is the sample commonly used in this pathology 2 .…”

“…Despite virus being more frequent in other upperway pathologies such as acute laryngitis, there have been reported cases of supraglottitis caused by Epstein−Barr Virus and parainfluenza A and, in half of our cases, the only isolated etiological agent in half of them was a virus. 3 Isolated pathogens from nasopharyngeal samples cannot confirm etiology due to the non-sterile zone; nevertheless, this is the sample commonly used in this pathology. 2 Therefore, special attention should be paid to the change in epidemiology and the presentation of the disease, which are different from the rapidly progressive course of classical epiglottitis.…”

“…Besides, epiglottitis due to other etiologies ( Streptococcus pyogenes , Streptococcus pneumoniae , Staphylococcus aureus , and Candida albicans ) has not increased, thus decreasing the overall incidence of epiglottitis 1 . Moreover, the cases described in the literature in the postvaccination era present clinical and etiological features different from those known so far 3 . Nevertheless, despite the decrease in incidence and the changes in etiology and presentation, it is still a life‐threatening condition, where an early diagnosis and a multidisciplinary approach are important.…”

“…1 Moreover, the cases described in the literature in the postvaccination era present clinical and etiological features different from those known so far. 3 Nevertheless, despite the decrease in incidence and the changes in etiology and presentation, it is still a life-threatening condition, where an early diagnosis and a multidisciplinary approach are important.…”

Epiglottitis (Supraglottitis)

“…Hib was replaced by A group betahemolytic streptococcus, streptococcus pneumoniae, and Staphylococcus aureus [2,11]. Particularly in children with immunodeficiency, rarely klebsiella, pseudomonas, candida, and viruses are also detected [1,12,13]. Noninfective causes include traumas on the upper respiratory tract, trauma from foreign bodies (injury by fishbone), and thermal burns [11,14].…”