Eccentric fixation patterns, clinical findings, and reading speed in patients with
            bilateral toxoplasmic macular retinochoroiditis

Antunes-Foschini, Rosália; Ho, Wanli; Messias, André

doi:10.5935/0004-2749.20180078

Cited by 4 publications

(5 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the literature, single/multiple PRL development in AMD has been reported at different rates (77%-100%), 1 , 6 , 7 , 8 and most are located extrafoveally. Greenstein et al 6 reported that all patients in their study developed a PRL, of which 73.3% were extrafoveal and 26.6% were foveal in location.…”

Section: Discussionmentioning

confidence: 99%

“… 31 While there are some studies suggesting that location may be relevant in terms of reading, 7 , 32 others showed no relationship between PRL location and reading speed. 2 , 33 , 34 Evidence indicates that PRLs are usually located to the left of the scotoma. 1 , 2 , 7 , 9 , 35 However, PRLs can develop in any retinal quadrant.…”

Section: Discussionmentioning

confidence: 99%

“…Microperimetry devices are currently used to evaluate the properties and stability of PRLs. 5 According to the literature, 77% to 100% of patients with central scotoma develop a PRL, 1 , 6 , 7 , 8 which is most commonly located in the nasal and superior retinal quadrants in AMD, 7 , 9 and fixation stability was shown to be associated with PRL to fovea and lesion margin distances, lesion size, and distance visual acuity. 1 , 6 , 9 , 10 Studies have also demonstrated a strong correlation between fixation stability and reading speed.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Fixation Stability and Preferred Retinal Locus in Advanced Age-Related Macular Degeneration

Altınbay¹,

İdil²

2022

tjo

View full text Add to dashboard Cite

Objectives: To evaluate fixation stability and characteristics of the preferred retinal locus (PRL) in patients with advanced age-related macular degeneration (AMD). Materials and Methods: Sixty-three eyes of 63 patients with AMD who presented to the low vision unit were included in this prospective study. Sociodemographic characteristics, eye examination findings, and reading performance results with the Minnesota Low Vision Reading test were evaluated. Microperimetry was used to evaluate fixation stability and PRL characteristics. Results: There was unstable fixation in 68% of the eyes, relative stable fixation in 27%, and stable fixation in 5%. The mean PRL-foveal distance was 5.15°±3.31° (range 0.75°-14.2°). PRL-foveal distance was greater in cases with unstable fixation than cases with stable fixation (p=0.023). Distance of the PRL from the lesion margin was not associated with absolute scotoma size or fixation stability (p=0.315, p=0.095, respectively). PRLs were most frequently located in the nasal quadrant (31%), followed by the superior quadrant (26%) of the retina. There was no significant relationship between PRL location and fixation stability (p=0.088). Fixation stability was significantly associated with reading speed (p=0.003). Conclusion: In advanced AMD, PRL-foveal distance is an important factor in fixation stability. Knowing the factors that affect fixation stability may be important in determining low vision rehabilitation strategies for these patients because of the strong association between fixation stability and reading speed.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Fixation Stability and Preferred Retinal Locus in Advanced Age-Related Macular Degeneration

Altınbay¹,

İdil²

2022

tjo

View full text Add to dashboard Cite

show abstract

“…This locus is known as preferred retinal locus, showing an association with the abnormal head position adopted by some patients during activities of daily living. 40 Another explanation, according to Mets et al, 39 is that, in some cases of extensive central lesions, an essential part of the macula might have been spared. We concluded that even in the presence of extensive macular lesions in a young child, it is not possible to predict the final visual function.…”

Section: Discussionmentioning

confidence: 99%

“…Just as in this study, the literature describes strabismus as the second most frequent ocular manifestation after retinochoroiditis and, quite often, this is the sign that alerts to an ocular lesion in a child without previous diagnosis of toxoplasmosis. 30,36,41 Antunes-Foschini et al 40 underscore the importance of rehabilitation and of rigorous follow-up since childhood, and the importance of stimulation of both eyes, as one cannot know which eye will be the dominant one when the visual system is fully developed.…”

Section: Discussionmentioning

confidence: 99%

Ocular Outcome of Brazilian Patients With Congenital Toxoplasmosis

Lago

Endres²,

Scheeren³

et al. 2020

Pediatric Infectious Disease Journal

View full text Add to dashboard Cite

Background: Retinochoroiditis is the most frequent manifestation of congenital toxoplasmosis. We aimed to describe the ocular outcome and factors that may influence the visual prognosis of these patients. Methods: Cohort of patients with confirmed congenital toxoplasmosis seen between 1996 and 2017 in Porto Alegre, southern Brazil. Results: Seventy-seven patients were included, of which 65 (85.5%) were identified by routine screening. Median age at the end of the follow-up was 10 years (minimum 2, maximum 25). Retinochoroiditis was present in 55 patients (71.4%). New retinochoroidal lesions developed after the first year of life in 77.8% of the patients who began treatment after the fourth month of life, compared with 35.2% among those treated before 4 months of life (relative risk = 0.45, 95% confidence intervals: 0.27-0.75, P = 0.02) and 33.3% among those treated before 2 months of life (relative risk = 0.42, 95% confidence intervals: 0.25-0.72, P = 0.01). There was a peak incidence of new retinochoroidal lesions between 4 and 5 years and another peak between 9 and 14 years, the latter only among girls. Thirty-four patients with retinochoroiditis were followed up for 10 years or more, and the school performance was appropriate in 28 (82.4%). Conclusions:The high incidence of new retinochoroidal lesions during the follow-up period indicates the importance of long-term follow-up of patients with congenital toxoplasmosis. Initiating treatment within the first 4 months of life, especially within the first 2 months, was a protective factor against the later development of retinochoroiditis. Despite the usual favorable prognosis, the high morbidity of congenital toxoplasmosis in Brazil was confirmed.

show abstract