Eccentric Left Ventricular Hypertrophy in Aortic Stenosis Caused by Unicuspid Aortic Valve

Abstract

decrescendo systolic murmur was heard at the second right intercostal space. Electrocardiogram showed left ventricular (LV) hypertrophy with normal QRS complexes. On transthoracic echocardiography the LV ejection fraction (LVEF)A 46-year-old man was referred to Ehime University Hospital for the treatment of refractory heart failure. On admission, blood pressure was 98/68 mmHg and heart rate was 92 beats/minute. A harsh crescendo- IMAGES IN CARDIOVASCULAR MEDICINE

Identification of Pathogenic Mutations for Dilated Cardiomyopathy Accompanied With Unicuspid Aortic Valve ― Reply ―

“…We appreciate Dr. Morita's and Dr. Komuro's interest in our study. 1 We concur with their comments. As stated by Dr. Morita, family history information is mandatory when caring for patients with dilated cardiomyopathy, whether familial or not.…”

Identification of Pathogenic Mutations for Dilated Cardiomyopathy Accompanied With Unicuspid Aortic Valve

“…1 The patient in this case suffered from refractory heart failure with enlarged LV end-diastolic diameter of 65 mm and reduced LV ejection fraction of 33%. It would be natural for the authors to consider the co-existence of "idiopathic" dilated cardiomyopathy (DCM) in this case, because the aortic stenosis caused by the unicuspid aortic valve could not explain well this obvious LV dilatation.…”

Unicuspid Aortic Valve: A Rare Congenital Anomaly

“…In adult population, the most common treatment modality is aortic valve replacement (AVR). Many require AVR in middle age, on average, in their third decade of life [2, 67]. In UAV, AVR is about 10–20 years earlier than BAV and 20–30 years earlier than TAV [5, 14, 16].…”