Eccrine angiomatous hamartoma with sudden enlargement and pain in an adolescent girl after menarche

Kikusawa, Ayuko; Oka, Masahiro; Taguchi, Kumiko; Shimizu, Hideki; Kunisada, Makoto; Nishigori, Chikako

doi:10.4161/derm.3.4.15365

Cited by 10 publications

(3 citation statements)

References 14 publications

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“…However, specific hormones have not been identified nor suggested. Pain in EAH has been attributed to small infiltrating nerves among the eccrine glands [16,17,18,19,20]. Our patients suffered the same experience, but the causes were unknown.…”

Section: Discussionmentioning

confidence: 65%

Eccrine Angiomatous Hamartoma: A Clinicopathological Study of 26 Cases

Sanusi

Li²,

Sun³

et al. 2015

Dermatology

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Background: Eccrine angiomatous hamartoma (EAH) is a rare benign cutaneous tumor characterized by the proliferation of eccrine glands and capillaries. Objective: The aim of this study was to summarize the clinicopathological characteristics of EAH. Methods: A retrospective chart review was performed on all patients diagnosed with EAH from 1977 to 2012 in the Union Hospital, Wuhan, P.R. China, and the clinicopathological features were compared with the cases reported in the literature. Results: A total of 26 patients with EAH were identified. The male:female ratio was 1.2:1. EAH most commonly presents as a solitary (80.8%) plaque (50.0%) on the lower extremities (61.5%). Most patients presented with hyperhidrosis localizing to the lesion. Although most patients did not have major pain or anatomic deformity, one patient had severe pain as well as difficulty walking and moving, necessitating leg amputation. The histopathological findings showed typical features of EAH. Conclusion: EAH is a rare but characteristically benign skin hamartomatous condition. In rare occasions it can be associated with severe structural and functional impairment.

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Section: Discussionmentioning

confidence: 65%

Eccrine Angiomatous Hamartoma: A Clinicopathological Study of 26 Cases

Sanusi

Li²,

Sun³

et al. 2015

Dermatology

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“…El color de estas es variable: puede ser rojo, violáceo, azul, amarillo o pardo o pueden verse combinaciones de colores (5) . Puede ser doloroso (infiltración de pequeños nervios) y estar asociado con hiperhidrosis, lo que puede ser útil en el diagnóstico (8) . Típicamente es de crecimiento lento, proporcional al crecimiento del paciente (1) .…”

Section: Manifestaciones Clínicasunclassified

Hamartoma ecrino angiomatoso una rara entidad

Arenas Sepúlveda,

Correa-Londoño,

MejíaBarreneche

et al. 2023

rev. asoc. colomb. dermatol. cir. dematol.

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El hamartoma ecrino angiomatoso está caracterizado por una proliferación de múltiples estructuras ecrinas y vasculares, generalmente se presentan desde el nacimiento, con crecimiento proporcional al individuo; como placas o nódulos solitarios o múltiples de coloración variable que afectan principalmente a las extremidades distales. Se desconoce la patogenia exacta, pero se han propuesto varias teorías, como la inducción anormal de dependencia heterotípica con malformación resultante de los elementos anexiales y mesenquimatosos. Se debe confirmar el diagnóstico con el estudio histopatológico, en donde se encontrará una neoplasia en la dermis media o profunda con proliferación de estructuras ecrinas y elementos vasculares pequeñas. Para los pacientes sintomáticos el tratamiento es la escisión quirúrgica.

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“…Finally in the tenth paper, Ayuko Kikuzawa et al 10 report the very interesting case of an Eccrine angiomatous hamartoma with sudden enlargement and pain in an adolescent girl after menarche.…”

mentioning

confidence: 99%

Hormones and skin: A never ending love story!

Reichrath¹

2011

Dermato-Endocrinology

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discuss the possible mechanisms by which vitamin D may have a therapeutic role in managing a variety of infections.In the second article Pisit Pitukcheewanont et al. 2 take a look at the interaction of skin and pancreas. They report an interesting case with Scleroderma-like skin changes (early morphea-type skin changes of the trunk and extremities) not involving the hand in a prepubertal male with type I diabetes mellitus. The authors explain that, to their knowledge there have been no reports of sclerodermalike skin changes, not affecting the hand in prepubertal patients with type I diabetes mellitus.In the following paper, Shwetha Thukuntla and Pratima Kumar 3 report on the effects of androgens on the skin. They present an interesting case with improvement of venous leg ulcers with androgen replacement therapy in a patient with undiagnosed Klinefelter syndrome.In the fourth article, Fatme Al Anouti et al. 4 demonstrate and discuss their surprising findings on vitamin D deficiency and sun avoidance among university students at Abu Dhabi, United Arab Emirates. They convincingly show that vitamin D deficiency could be a major public health burden among young Emirati adults, mostly because of sun deprivation in a sun-blessed country. Their study included a random sample of 138 females and 70 males tested for serum 25-hydroxyvitamin D [25(OH)D] status. To further evaluate the predictors of vitamin D status in this population, the authors examined diet, obesity and sun exposure. In summer, the mean serum 25(OH)D concentration for females was 20.9 ± 14.9 nmol/L, whereas that for males was 27.3 ± 15.7 nmol/L. Females scored significantly higher than males on the sun avoidance inventory (SAI), indicating that females avoid sun exposure to a greater extent than males, possibly explaining the lower vitamin D status. Moreover, the authors reported that a significant negative correlation also existed between SAI and vitamin D status (Pearson's r = -0.33; p < 0.01), but no significant association was evident between vitamin D status and body mass index (Pearson's r = 0.03; p = 0.33) or low dietary intake of vitamin D-fortified foods (Pearson's r = 0.08; p = 0.13). The mean serum 25(OH)D concentration for females tested in winter was 31.3 ± 12.3 nmol/L while in the summer, it was 20.9 ± 14.9 nmol/L. This difference was statistically significant, suggesting that seasonal variation plays an important role in vitamin D status in the United Arab Emirates. The authors concluded that fortification of foods and drinks with vitamin D, supplementation and sensible sun exposure are important steps toward minimizing vitamin D deficiency.In the following article, Jörg Dötsch 5 analyzes the association of low birth weight, bone metabolism and fracture risk. HeThe human skin is a fascinating organ, representing both the site of production of a multitude of different hormones and an important target tissue for their pleiotropic biologic effects. Correlatives for many of the classical endocrine pathways, including parathyroid hormone relate...

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Eccrine angiomatous hamartoma with sudden enlargement and pain in an adolescent girl after menarche

Cited by 10 publications

References 14 publications

Eccrine Angiomatous Hamartoma: A Clinicopathological Study of 26 Cases

Eccrine Angiomatous Hamartoma: A Clinicopathological Study of 26 Cases

Hamartoma ecrino angiomatoso una rara entidad

Hormones and skin: A never ending love story!

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