Eccrine porocarcinoma of the lower extremity: A case report and review of literature

Abstract

Eccrine porocarcinoma is a rare malignancy of the eccrine sweat gland. It is usually found frequently on the lower extremities, and it affects both sexes equally usually in the sixth to seventh decade. In our case, we present a 42-year-old male patient with a recurring exophytic tumor on the right lower extremity without local extension. The initial tumor was biopsied, excised and diagnosed as an eccrine poroma. The tumor then recurred 6 years later, was re-excised, reconstructed with a soleus muscle flap and diagnosed as an eccrine porocarcinoma.

Eccrine Porocarcinoma of the Scalp: A Case Report and Review of Literature

“…The most common presentation is either as reddish mass or nodule that may ulcerate, become itchy and/or painful and may spontaneously bleed [9]. It commonly arises in the lower extremities "legs and feet", trunk, head and neck and upper extremities 10,11]. It rarely occurs in scalp, face, ear, eye lid and genitalia [2,11].…”

“…Lymph nodes dissection is to be considered in case of regional lymph node involvement [10]. Arslan et al recommended the use of adjuvant local radiotherapy to reduce local recurrence, especially when margins are close [16].…”

A Case of Recurrent Eccrine Porocarcinoma with Regional Lymph Nodal Metastasis, Arising on a Bowen’s Disease Patch

“…It mostly affects men and women equally in their sixth to seventh decade [1]. Only less than 300 cases have been reported so far [1].…”

“…It mostly affects men and women equally in their sixth to seventh decade [1]. Only less than 300 cases have been reported so far [1]. It may arise as a primary sweat gland tumor or result from malignant transformation of an eccrine poroma [2].…”

“…Adjuvant radiotherapy; single or multi-agent chemotherapy with isotretinoin, interferon alfa, methotrexate, cisplatin, bleomycin, adriamycin, paclitaxel, or tegafur; and electro chemotherapy have been reported with varying responses [1,8]. …”