Eccrine spiradenoma: A rare adnexal tumor

Singh, Kanwaljeet; Chatterjee, Tathagatta

doi:10.4103/ijc.ijc_301_17

Cited by 13 publications

(37 citation statements)

References 7 publications

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“…Pain is manifested due to irritation of nervous plexus in the dermis and subcutaneous layer. 3,7 Histopathology is definitive for diagnosis and is characterized by encapsulated collection of two types of cells arranged in pseudotubular pattern and dilated vascular channels. 3 The outer layer consists of small cells with darkly staining hyperchromatic nuclei surrounding the inner layer consisting of larger cells with eosinophilic cytoplasm.…”

Section: Discussionmentioning

confidence: 99%

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Imaging findings of rare plantar eccrine spiradenoma

Nepal

Alam

Rodrigue

et al. 2021

Foot & Ankle Surgery: Techniques, Reports & Cases

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Eccrine spiradenoma (ES) is a rare benign tumor of the eccrine sweat gland typically located in the dermis and subcutaneous layers of the skin. Recent literature suggests they typically arise from proximal torso and upper extremities and commonly present as painful subcutaneous nodules. Given its scarcity, imaging findings are not well established. We report an interesting case of plantar eccrine spiradenoma describing its imaging features and closest differentials.

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Section: Discussionmentioning

confidence: 99%

“…2 97% of ES are solitary and more than 80% of the tumors are proximal arising above the level of costal margins. 3,4 In the existing literature, only a few studies have described the imaging features of ES. 2,5 Case Report A 32-year-old male presented to the orthopedic clinic with gradually progressive painful swelling on the medial plantar surface of midfoot.…”

mentioning

confidence: 99%

Imaging findings of rare plantar eccrine spiradenoma

Nepal

Alam

Rodrigue

et al. 2021

Foot & Ankle Surgery: Techniques, Reports & Cases

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“…Similar to cylindromas, they contain two types of cells: some small, basaloid cells with hyperchromatic nuclei, located in the periphery of the lobules, and some which are larger, pale with ovoid nuclei and conspicuous nucleolus-present in the center of the islands. The tumor may contain duct-like structures of unknown differentiation and cystic cavities filled with finely granular eosinophilic material [21]. Occasionally, the tumors develop near a nerve trunk.…”

Section: Discussionmentioning

confidence: 99%

Observations on Four Cases of Brooke–Spiegler Syndrome

Leventer¹,

Coltoiu²,

Zota³

et al. 2020

Reports

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Background: Brooke–Spiegler Syndrome is a rare genetic autosomal dominant disorder with variable penetrance. Its main feature consists of the development of multiple adnexal tumors that originate from the follicular-sebaceous-apocrine unit, most commonly: cylindromas, trichoepitheliomas and spiradenomas. Case presentation: We present four cases of Brooke–Spiegler Syndrome found in our clinic, as well as their clinicopathological traits and the surgical techniques used in their management. The familial history of three of the presented cases supports the genetic component of the disease. Cylindromas, spiradenomas and trichoepitheliomas coexisted in one of the cases presented. The therapeutic options used were electrocautery, CO2 laser, as well as tumor debulking followed by closure with metal staples. Discussion: The treatment remains a challenge and must be individualized based on the type, location and number of the lesions. Conservative methods such as CO2 laser and tumor debulking accompanied by closure with metal staples remain a viable option taking into account the large number of lesions. As patients usually develop multiple neoplasms throughout their lifetime, repeated procedures may be needed. Conclusion: Considering the few numbers of Brooke–Spiegler syndrome cases in the current literature, the authors report these patients in order to increase awareness and to help establish the most appropriate approach in managing the disease.

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“…[8] Once malignant, spiradenocarcinomas have a metastasis rate of 50% spreading most commonly to the lymph nodes, bone, lungs, brain, and liver. [1,9] Adding to the difficulty of spiradenoma differentiation, a biopsy is required for diagnosis but can be recommended against in cases like epidermal cysts as nodule penetration can lead to leakage of cyst contents generating inflammation. [10] Imaging has been utilized as diagnostic aid.…”

Section: Discussionmentioning

confidence: 99%

“…The characteristics of both tumors in all reported cases in the literature over the past 76 years are displayed in Table 1. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18][19]…”

Section: Introductionmentioning

confidence: 99%

Spiradenoma of the breast and review of cases over 76-years

Dick

Sharma

2019

CRCP

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Spiradenomas stem from eccrine and apocrine glands to form benign cutaneous tumors. When arising on the breast, nipple, and areola region, spiradenomas can be difficult to differentiate from more worrisome breast masses. This is particularly true in patients with a prior history of breast cancer. These tumors can be mimicked by a wide range of adnexal growths and play a role in syndromic conditions. We present a case of a 56-year-old female with a 20-year enlarging left lower inner quadrant breast mass reviewed on mammography which was later excised and histopathologically diagnosed as a spiradenoma. Spiradenomas can be challenging to diagnose as they can present with similar findings on inexpensive and non-invasive testing such as ultrasound and mammogram. While a biopsy is a definitive tool for diagnosis, this is contraindicated in some spiradenoma mimickers such as epidermal cysts complicating diagnosis. To our knowledge, there are only six case reports of breast spiradenomas. We have reviewed the histopathology of this case and summarized all cases of breast spiradenomas and their malignant counterpart spiradenocarcinomas available in the literature compiling their presentations and imaging findings.

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Eccrine spiradenoma: A rare adnexal tumor

Cited by 13 publications

References 7 publications

Imaging findings of rare plantar eccrine spiradenoma

Imaging findings of rare plantar eccrine spiradenoma

Observations on Four Cases of Brooke–Spiegler Syndrome

Spiradenoma of the breast and review of cases over 76-years

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