Advances in sampling and coding theory have contributed significantly towards lowering power consumption of resource-constrained devices, e.g. battery-operated sensor nodes, enabling them to operate for extended periods of time. In this paper, rate and energy efficiency of a recently proposed adaptive nonuniform sampling framework by Feizi et al., called Time-Stampless Adaptive Nonuniform Sampling (TANS), is examined and compared against state-of-the-art methods. TANS addresses one of the main limitations of nonuniform sampling schemes: sampling times do not need to be stored/transmitted since they can be computed using a function of previously taken samples. The sampling rate is adapted continuously with the aim of reducing the rate and therefore the energy consumption of the sampling process when the signal is varying slowly. Three TANS methods are proposed for different signal models and sampling requirements: i) TANS by polynomial extrapolation, which only assumes the third derivative of the signal is bounded but requires no other specific knowledge of the signal; ii) TANS by incremental variation, where the sampling time intervals are chosen from a lattice; and iii) TANS constrained to a finite set of sampling rates. Practical implementation details of TANS are discussed, and its rate and energy performance are compared with uniform sampling followed by a transformation-based compression, nonuniform sampling, and compressed sensing. Our results demonstrate that TANS provides significant improvements in terms of both the rate-distortion performance and the energy consumption compared against the other approaches.Index Terms-Nonuniform sampling, energy efficient acquisition schemes, compressed sensing, adaptive sampling for biomedical applications.