Echocardiographic Assessment of Large Artery Stiffness

Chirinos, Julio A.

doi:10.1016/j.echo.2016.09.004

Cited by 6 publications

(2 citation statements)

References 26 publications

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“…In addition to VaSera-based measurements of arterial stiffness, the echocardiographic protocol also included pulsed wave Doppler acquisitions of the LV outflow tract and proximal abdominal aorta, which can be used to compute thoracic aortic transit time and pulse wave velocity, pending the ongoing development of regression equations to estimate aortic length. 30…”

Section: Echocardiography Protocol and Quantitationmentioning

confidence: 99%

Multi-Ethnic Study of Atherosclerosis Early Heart Failure Study: Rationale, Design, and Baseline Characteristics

Beussink-Nelson,

Freed,

Chirinos

et al. 2024

Circ: Heart Failure

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Background: Current prevalence estimates of heart failure (HF) are primarily based on self-report or HF hospitalizations. There is an unmet need to define the prevalence and pathogenesis of early symptomatic HF, which may be undiagnosed and precedes HF hospitalization. Methods: The MESA (Multi-Ethnic Study of Atherosclerosis) Early HF study was conducted during MESA exam 6 to determine the prevalence of early HF and investigate the transition from risk factors to early HF in a diverse population-based cohort of older adults. Between 2016 and 2018, 3285 MESA participants from 6 field centers underwent comprehensive speckle-tracking echocardiography with passive leg raise maneuver, Kansas City Cardiomyopathy Questionnaire, 6-minute walk test, arterial stiffness assessment, and proteomics (including NT-proBNP [N-terminal pro-B-type natriuretic peptide]). Results: Median age was 73 (25th–75th percentile 67–81) years, 53.2% were female, 25.6% were Black, 12.8% were Chinese, and 40.0% were White. The prevalence of HF risk factors was high: hypertension, 61.9%; former or current smoking, 53.7%; obesity 34.8%; diabetes; 24.7%; and chronic kidney disease; 22%. Overt cardiovascular disease, which ranged from 2.1% (HF) to 13.6% (atrial fibrillation), was less common. Of the 3285 participants, 96% underwent proteomics, 94% Kansas City Cardiomyopathy Questionnaire, 93% speckle-tracking echocardiography with passive leg raise, 82% arterial stiffness exam, and 77% 6-minute walk test. Feasibility of resting speckle-tracking echocardiography (87%–99% across cardiac chambers) and passive leg raise Doppler/speckle-tracking echocardiography (>84%) measurements was high. A total of 120 unique echocardiographic indices were measured. Conclusions: The MESA Early HF study is a key resource for cardiovascular researchers who are interested in improving the epidemiological and phenotypic characterization of early HF. REGISTRATION: URL: https://www.clinicaltrials.gov ; Unique identifier: NCT00005487.

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Section: Echocardiography Protocol and Quantitationmentioning

confidence: 99%

Multi-Ethnic Study of Atherosclerosis Early Heart Failure Study: Rationale, Design, and Baseline Characteristics

Beussink-Nelson,

Freed,

Chirinos

et al. 2024

Circ: Heart Failure

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“…Arterial stiffness can be assessed by various non-invasive methods such as applanation tonometry, echocardiography, and magnetic resonance imaging [ 12 ]. Echocardiography is the most widely used imaging technique in clinical CV practice [ 13 ]. Echocardiography‑derived indices, including simple M-mode-derived measurements, may be more reliable, as central arterial elasticity is more important than peripheral arterial elasticity in predicting the CV outcome [ 14 ].…”

Section: Introductionmentioning

confidence: 99%

Relation between aortic elasticity parameters and SYNTAX score in postmenopausal diabetic women

Naseem

Alaarag

2023

Egypt Heart J

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Background Postmenopausal women are at increased risk of coronary artery disease (CAD). Diabetes Mellitus is a major risk factor for CAD. The stiffening of the aorta is associated with increased cardiovascular morbidity and mortality. We aimed to investigate the relation of aortic elasticity parameters to CAD severity assessed by SYNTAX score (SS) in diabetic postmenopausal women. The study prospectively included 200 consecutive diabetic postmenopausal women with CAD who underwent elective coronary angiography. Patients were classified into 3 groups based on SS, low-SS ≤ 22, intermediate-SS ≥ 23– ≤ 32, and high-SS ≥ 33. Echocardiographic aortic elasticity parameters, including aortic stiffness index (ASI), aortic strain (AS) (%) and aortic distensibility (AD) were obtained in all patients. Results Patients in the high SS group were older age and had a higher aortic stiffness. After adjusting different co-variates AD, AS, and ASI could be used as independent predictors of high SS with the following P-values (0.019, 0.016 and 0.010) and cut-off values (2.5, 3.6 and 2.9), respectively. Conclusions In diabetic postmenopausal women, the simple echocardiography-derived aortic elasticity parameters might predict the severity and complexity of angiographic coronary lesions assessed by the SS.

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Arterial stiffness and pulsatile hemodynamics in coronary artery disease and other forms of atherosclerotic vascular diseases

Hashimoto

2022

Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease

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Echocardiographic Assessment of Large Artery Stiffness

Cited by 6 publications

References 26 publications

Multi-Ethnic Study of Atherosclerosis Early Heart Failure Study: Rationale, Design, and Baseline Characteristics

Multi-Ethnic Study of Atherosclerosis Early Heart Failure Study: Rationale, Design, and Baseline Characteristics

Relation between aortic elasticity parameters and SYNTAX score in postmenopausal diabetic women

Arterial stiffness and pulsatile hemodynamics in coronary artery disease and other forms of atherosclerotic vascular diseases

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