Echocardiographic Estimation of Pulmonary Artery Pulsatility Index in Pulmonary Hypertension

Mirza, Sara; Khalif, Adnan; Khodjaev, Soidjon; Alpert, Craig; Raina, Amresh; Kanwar, Manreet; Murali, Srinivas; Benza, Raymond L.; Hadi, Azam

doi:10.1016/j.healun.2019.01.1252

The Journal of Heart and Lung Transplantation

2019

DOI: 10.1016/j.healun.2019.01.1252

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Echocardiographic Estimation of Pulmonary Artery Pulsatility Index in Pulmonary Hypertension

Sara Mirza

Adnan Khalif

Soidjon Khodjaev

et al.

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“…is a novel useful index for assessment of RV function, that can be measured not only by right heart catheterization but also by echocardiography, as presented recently. 3,4 Noninvasive assessment of the PAPi would make the examination more accessible and more widely usable.…”

mentioning

confidence: 99%

Optimal therapeutic strategy for postinfarction ventricular septal defect

Artemiou

Gašparovič

Hudec

et al. 2022

Journal of Cardiac Surgery

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mentioning

confidence: 99%

Optimal therapeutic strategy for postinfarction ventricular septal defect

Artemiou

Gašparovič

Hudec

et al. 2022

Journal of Cardiac Surgery

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Use and Implications of Echocardiography in the Hemodynamic Assessment of Cardiogenic Shock

Simeoli

Moscardelli

Urbani

et al. 2023

Current Problems in Cardiology

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Invasive haemodynamics predict outcomes in paediatric pulmonary artery hypertension

Natarajan,

Rodgers,

Narasimhan

et al. 2024

Cardiol Young

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Background: Invasive haemodynamics are often performed for initiating and guiding pulmonary artery hypertension therapy. Little is known about the predictive value of invasive haemodynamic indices for long-term outcomes in children with pulmonary artery hypertension. We aimed to evaluate invasive haemodynamic data to help predict outcomes in paediatric pulmonary artery hypertension. Methods: Patients with pulmonary artery hypertension who underwent cardiac catheterisation (2006–2019) at a single centre were included. Invasive haemodynamic data from the first cardiac catheterisation and clinical outcomes were reviewed. The combined adverse outcome was defined as pericardial effusion (due to right ventricle failure), creation of a shunt for pulmonary artery hypertension (atrial septal defect or reverse Pott’s shunt), lung transplant, or death. Results: Among 46 patients with a median [interquartile range (IQR)] age of 13.2 [4.1–44.7] months, 76% had CHD. Median mean pulmonary artery pressure was 37 [28–52] mmHg and indexed pulmonary vascular resistance was 6.2 [3.6–10] Woods units × m2. Median pulmonary artery pulsatility index was 4.0 [3.0–4.7] and right ventricular stroke work index was 915 [715–1734] mmHg mL/m2. After a median follow-up of 2.4 years, nine patients had a combined adverse outcome (two had a pericardial effusion, one underwent atrial level shunt, one underwent reverse Pott’s shunt, and six died). Patients with an adverse outcome had higher systolic and mean pulmonary artery pressures, higher diastolic and transpulmonary pressure gradients, higher indexed pulmonary vascular resistance, higher pulmonary artery elastance, and higher right ventricular stroke work index (p < 0.05 each). Conclusion: Invasive haemodynamics (especially mean pulmonary artery pressure and diastolic pressure gradient) obtained at first cardiac catheterisation in children with pulmonary artery hypertension predicts outcomes.

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Echocardiographic Estimation of Pulmonary Artery Pulsatility Index in Pulmonary Hypertension

Cited by 3 publications

References 0 publications

Optimal therapeutic strategy for postinfarction ventricular septal defect

Optimal therapeutic strategy for postinfarction ventricular septal defect

Use and Implications of Echocardiography in the Hemodynamic Assessment of Cardiogenic Shock

Invasive haemodynamics predict outcomes in paediatric pulmonary artery hypertension

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