Echocardiographic parameters of atrial cardiopathy and the detection of atrial fibrillation in patients with cryptogenic stroke

Gil, Á. Lambea; Meza, H. Tejada; Perales, Carlos Rubén López; Roy, Jayanta; Moreno, J. Marta

doi:10.1016/j.nrleng.2017.12.013

Cited by 1 publication

(1 citation statement)

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“…In previously published studies, LA enlargement was commonly evaluated by LA anteroposterior diameter which is an inappropriate tool since enlargement is usually asymmetrical and not in an anteroposterior direction [ 19 ]. Furthermore, it does not provide information about the LA function.…”

Section: Introductionmentioning

confidence: 99%

Atrial cardiopathy in young adults with embolic stroke of undetermined source: a myocardial deformation imaging analysis

Pires

Silva

Garcia

et al. 2022

Int J Cardiovasc Imaging

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Background Atrial cardiopathy (AC) has emerged as a potential pathological thrombogenic atrial substract of embolic stroke of undetermined source (ESUS), even in the absence of atrial fibrillation. Left atrium (LA) myocardial deformation analysis may be of value as a subclinical marker of AC and a predictor of ESUS. Aims To compare LA mechanical function between ESUS cases and age and sex-matched controls. Methods A single-center analytical study with case-control design was performed. Case group was composed by young patients admitted in the Neurology department from January 2017 to June 2021. Control group was composed by age and sex matched controls recruited from the community. All participants performed echocardiogram and a smaller sample underwent cardiac magnetic resonance. Results We recruited 31 ESUS patients aged between 18 and 65 years and 31 age and sex matched controls. ESUS patients had a significantly higher prevalence of cardiovascular risk factors and patent foramen ovale (PFO). The prevalence of AC was not different between groups. Echocardiogram parameters, including strain analysis, were similar between groups, except for LA appendage (LAA) ostium variation which was significantly lower in ESUS patients (absolute: 6.5vs8.7mm, p<0.001; relative: 44.5%vs53.4%, p=0.002). After exclusion of patients with PFO, all the results were statistically similar. Regarding cardiac magnetic resonance analysis, there were no statistically significant differences between groups. Conclusion This study shows that in our population atria cardiopathy and atrial function was not associated with ESUS.LAA structural and functional abnormalities may play a major role. The role of LAA in ESUS warrants further studies.

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Section: Introductionmentioning

confidence: 99%