Echocardiography in the Assessment of Patients with Rheumatologic Diseases

Al-Mohaissen, Maha A.; Chan, Kwan‐Leung

doi:10.1007/s11886-016-0757-2

Cited by 11 publications

(10 citation statements)

References 63 publications

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“…Many imaging tools such as coronary artery calcification by multi-slice computed tomography [39], intima–media thickness by carotid ultrasound [40], arterial stiffness with aortic pulse wave velocity or arterial augmentation index, ankle–brachial index [41–43], and echocardiography [44], have been proposed to measure subclinical vascular damage in RA. Among these, only carotid ultrasound has been included in EULAR recommendations for clinical practice, based on the evidence that carotid plaques in RA are associated with disease duration, disease activity, and ischemic heart disease with poor CVD-free survival [45–47].…”

Section: Introductionmentioning

confidence: 99%

Practical Management of Cardiovascular Comorbidities in Rheumatoid Arthritis

et al. 2017

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Cardiovascular (CV) comorbidities are a frequent extra-articular manifestation of rheumatoid arthritis (RA). Cardiovascular disease (CVD) with accelerated atherosclerosis is a major cause of morbidity and mortality in patients with RA. Subclinical CVD may be present since the early phase of RA. Not only traditional but also non-traditional CV risk factors are involved in the pathogenesis of RA-related CVD. Due to the lack of specifically designed randomized clinical trials, it is still unclear which tools to use to perform CV risk assessment, how to interpret the results and which interventions are appropriate in RA patients both to prevent and to manage CVD. Based on the available evidence, we propose a practical approach.

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Section: Introductionmentioning

confidence: 99%

Practical Management of Cardiovascular Comorbidities in Rheumatoid Arthritis

et al. 2017

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“…In RA patients, the asymptomatic reduction in cardiac systolic function is about 3 times more than non-RA population 24 . Study has suggested that RA patients with reduced LVEF% are less likely received antirheumatic drugs such as methotrexate and corticosteroids 26 .…”

Section: Discussionmentioning

confidence: 96%

“…Valvular abnormalities mainly involving the mitral and aortic valve with mild to moderate regurgitation in RA patients 24 , the mechanisms might be due to the chronic inflammatory process and fibrosis of the cardiac valves 25 . Our results showed that the prevalence of mitral regurgitation was slightly more than that of the control group, but the difference was not significant between 2 groups, we found the prevalence of mitral regurgitation was correlated with ESR in RA patients.…”

Section: Discussionmentioning

confidence: 99%

Features of cardiac remodeling in Patients with Acute Coronary Syndrome Complicated with Rheumatoid Arthritis

Pan

Wang

2017

Sci Rep

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Cardiovascular diseases are important factors to increased morbidity and mortality in patients with rheumatoid arthritis (RA). The aim of this study is to investigate the effects of RA on cardiac remodeling in patients with acute coronary syndrome (ACS). Sixty-one patients with ACS complicated with RA (RA group) and 55 age- and sex-matched patients with ACS without RA (control group) were enrolled. We compared the parameters of laboratory and echocardiogram across the 2 groups. Levels of serum brain natriuretic peptide in patients with RA were significantly higher than control group. Prevalence of left ventricular hypertrophy (LVH), and LV diastolic dysfunction (E/A < 1) were significantly higher in the RA patients, while the LV ejection fraction (EF%) was significantly lower in RA patients. Incidence of tricuspid regurgitation and pulmonary regurgitation were significantly higher in ACS patients with RA than in the ACS patients without RA. In RA group, levels of serum high density lipoprotein cholesterol were negatively correlated with C reactive protein (CRP), EF% was also negatively correlated with CRP. The prevalence of LVH and mitral regurgitation showed positive correlations with ESR. Early intervention for controlling the inflammation associated with RA can play a significant role in preventing cardiac remodeling in ACS patients.

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“…Moreover, 24 h-Holter, 2-dimensional speckle tracking imaging, nuclear angiography, and cardiovascular magnetic resonance could provide more valuable information for discovering early CI in patients with SSc. [13,17,18] We did not schedule too many medical assessments. Rapid targeted treatment (a pacemaker implantation) was administered after a definitive diagnosis to prevent adverse cardiovascular events.…”

Section: Discussionmentioning

confidence: 99%