The role of technology in ecosystem partnerships is to augment local skills and capacity in health services delivery, and to better connect information and health professionals in a way that enables them to take on new roles to help each other. Technology over the past three decades has resulted in dramatic acceleration in the progression from open surgery to minimally invasive, image-guided therapy (IGT). Today, imaging technologies like X-ray and ultrasound allow real-time, in-body visualization of instruments and anatomy without the need for surgical incisions. These advancements coupled with the ongoing miniaturization of endovascular and percutaneous devices have allowed interventional physicians to perform procedures often without general anesthesia and via incisions no larger than a few millimeters. This results in patient recoveries measured in hours to days, rather than weeks as seen with traditional open surgical repairs. Reduced costs, faster recoveries and shortened hospitalization stays are powerful enablers towards capacity building, empowering hospitals to treat more patients per day. Still, new and different skills will be required for doctors, nurses and technologists to perform and support image-guided interventions and minimally invasive surgery and to operate the sophisticated imaging systems, medical devices, and implants that are the backbone of these procedures. This chapter will describe how technologies like extended reality and robotics can be enablers of capacity building in LMIC, if enabled by a strong ecosystem partnership.