ECHOVIST-200 enhanced hystero-sonography

Tamási, F.; Weidner, András; Domokos, N; Bedros, Róbert J.; Bagdány, S

doi:10.1016/j.ejogrb.2005.01.006

Cited by 18 publications

(5 citation statements)

References 9 publications

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“…By means of CnTI-SonoVue-HyCoSy, we obtained a sensitivity and specificity of 87% and 84%, respectively. Our results are in agreement with other investigators who reported their findings on smaller series [ 16 , 17 ], showing that positive contrast agents are more efficient than saline solution. In addition to this, our results show that the use of second-generation contrast media does not require a learning period as observed in our series for air/saline-HyCoSy [ 17 ].…”

Section: Discussionsupporting

confidence: 94%

“…Our results show that the kappa value of CnTI-SonoVue HyCoSy reaches an efficient agreement (kappa 0.66) with the final diagnosis, whereas the traditional air/saline-Hy-CoSy yielded a kappa value of 0.52, corresponding to moderate agreement with the reference standard. This latter value obtained by air/saline-HyCoSy confirms most of the literature reporting these techniques [ 11 – 16 ]. The very high normal predictive value (95%) of air/saline-HyCoSy may suggest that this procedure can be performed as a screening examination to avoid the use of more expensive contrast media.…”

Section: Discussionsupporting

confidence: 86%

See 1 more Smart Citation

Ultrasound in Infertility Setting: Optimal Strategy to Evaluate the Assessment of Tubal Patency

Mandia

Personeni

Antonazzo

et al. 2017

BioMed Research International

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Tubal patency is a key element in women who are undergoing assisted reproductive techniques (ART), in order to attempt or exclude intrauterine insemination (IUI) cycles. Amongst the different procedures that can be used, without resorting to laparoscopy that remains the gold standard, hystero-salpingo-contrast sonography (HyCoSy) is an acceptable, time-efficient, and well tolerated option; it can be performed with administration of saline and air simultaneously or alternately (air/saline-HyCoSy), or with some other contrast agents, like SonoVue (sulfur hexafluoride microbubbles). In this paper, we describe two different studies: in the first one, our aim is to compare the efficiency of air/saline-HyCoSy with HyCoSy performed with contrast media (SonoVue), considering hysterosalpingography (HSG) and laparoscopy (LPS) as reference tests; in the second one, we estimate the pregnancy rate of a cohort of infertile women selected to undergo IUI cycles after tubal bilateral patency demonstration with air/saline-HyCoSy, to understand if this technique can be used as an efficient screening procedure in a Reproductive Unit.

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Section: Discussionsupporting

confidence: 94%

Section: Discussionsupporting

confidence: 86%

Ultrasound in Infertility Setting: Optimal Strategy to Evaluate the Assessment of Tubal Patency

Mandia

Personeni

Antonazzo

et al. 2017

BioMed Research International

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“…The movement of a suspension of air bubbles through the fallopian tubes can be visualized during HyCoSy after intratubal instillation of products like Echovist or Levovist (Schering AG, Berlin, Germany) and SonoVue (Bracco International BV, Amsterdam, The Netherlands). The use of these products, which consist of a suspension of micron-sized air bubbles in an aqueous galactose solution [6,7,8,9,10], is limited by restricted commercial availability and high cost. A cheap but highly operator-dependent reported alternative for these products during HyCoSy is to use an alternated injection of water and air in the uterine cavity and to sonographically detect air bubbles around the ovary and free fluid in the cul-de-sac [11,12,13].…”

Section: Introductionmentioning

confidence: 99%

The Use of a New Gel Foam for the Evaluation of Tubal Patency

Schoubroeck

Bosch

Meuleman

et al. 2012

Gynecol Obstet Invest

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Aims: To evaluate the feasibility and the reliability of hysterosalpingo-foam sonography (HyFoSy) using gel foam in the assessment of tubal patency. Methods: Nonrandomized, observational, academic and single-center study of 20 women being investigated because of subfertility and scheduled for a laparoscopy with chromopertubation. A detailed description of HyFoSy with a newly developed gel foam is given in the way it proved to be most efficient in our hands. The results of HyFoSy are compared to the data regarding tubal patency testing during laparoscopy by chromopertubation. Results: All 20 HyFoSy were technically successful. Four of the 40 tubes, 1 right tube and 3 left tubes, were not patent at HyFoSy (3 tubes with proximal block and 1 tube with distal block). There was a 100% agreement between tubal patency data according to HyFoSy testing and laparoscopic chromopertubation testing. Conclusion: HyFoSy is both feasible and accurate in the diagnosis of tubal patency.

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“…Again, these all have their own limitations. Echovist may cause galactose allergies due to its galactose preparation; furthermore, it only has a short effect; within 5 minutes, its dissolution may result in poor visualization [5]. Because of its strong oxidizing ability, hydrogen peroxide may cause irritation and impair the mucosa.…”

Section: Introductionmentioning

confidence: 99%

Combined Real-Time Three-Dimensional Hysterosalpingo-Contrast Sonography with B Mode Hysterosalpingo-Contrast Sonography in the Evaluation of Fallopian Tube Patency in Patients Undergoing Infertility Investigations

Sumin

Chen

et al. 2019

BioMed Research International

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Objective. This prospective study aimed to investigate the use of real-time three-dimensional hysterosalpingo-contrast sonography (4D-HyCoSy), using contrast agent SonoVue, with B mode hysterosalpingo-contrast sonography (B mode-HyCoSy), to evaluate tubal patency and the wall of the Fallopian tubes in infertility patients. Method. In total, we recruited 739 women with fertility requirements from the First Affiliated Hospital of Shantou Medical College between January 2017 and July 2018. All cases received 4D-HyCoSy using contrast agent SonoVue, immediately followed by the B mode-HyCoSy. Of these patients, 145 showed pathological findings in the Fallopian tubes during HyCoSy; 34 of these (62 Fallopian tubes) were verified by laparoscopy and the dye test against routine reference standards. Sonographic findings, along with laparoscopic findings and dye test results, were used to compare the two techniques using the Cohen kappa coefficient. We also investigated the duration of examination and pain score. Results. Compared with laparoscopy and the dye test, the tubal occlusion diagnostic accordance rates for 4D-HyCoSy were 88.7% (32+23)/62, with a kappa coefficient of 0.769 and a 76.9% agreement rate. Distal occlusion diagnostic accordance rates for 4D-HyCoSy were 100% (8/8) with a k coefficient of 1.000 and a 100% agreement rate. Conclusions. The use of 4D-HyCoSy, with B mode-HyCoSy, for the diagnosis of tubal patency is safe, feasible, noninvasive, and highly accurate. B mode-HyCoSy allowed us to observe tubal walls in an intuitive manner.

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ECHOVIST-200 enhanced hystero-sonography

Cited by 18 publications

References 9 publications

Ultrasound in Infertility Setting: Optimal Strategy to Evaluate the Assessment of Tubal Patency

Ultrasound in Infertility Setting: Optimal Strategy to Evaluate the Assessment of Tubal Patency

The Use of a New Gel Foam for the Evaluation of Tubal Patency

Combined Real-Time Three-Dimensional Hysterosalpingo-Contrast Sonography with B Mode Hysterosalpingo-Contrast Sonography in the Evaluation of Fallopian Tube Patency in Patients Undergoing Infertility Investigations

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