Eclampsia: A five-year retrospective review in Sagamu, South-West Nigeria

Odelola, Oluwaseyi Isaiah; Akadri, Adebayo; Akinpelu, Akintunde; Elegbede, M.; Ogunyemi, John; Popoola, M

doi:10.4103/njm.njm_73_20

Cited by 4 publications

(10 citation statements)

References 10 publications

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“…This is not unusual for a nation like Nigeria that has low and moderate income levels and antenatal care facilities that are inadequate. The majority of the women had antepartum eclampsia, which is consistent with findings from other studies conducted in this region of the world [10][11][12], but not with data from high-income nations where postpartum eclampsia is more typical [8]. Improvements in prenatal care, screening and early preeclampsia identification, and the preventive use of magnesium sulphate in the treatment of severe preeclampsia in high-income nations have all been credited with this [8].…”

Section: It Is Not Entirely Apparent What Causes Seizures In Pregnantsupporting

confidence: 84%

“…Only a minority of the women with eclampsia were booked patients in similar studies from other regions of the country, with the majority of patients being unbooked [2,10,12]. Recent years have seen an increase in the promotion of prevention through the identification of those who are at risk and early preeclampsia detection [10,12].…”

Section: It Is Not Entirely Apparent What Causes Seizures In Pregnantmentioning

confidence: 99%

“…Improvements in prenatal care, screening and early preeclampsia identification, and the preventive use of magnesium sulphate in the treatment of severe preeclampsia in high-income nations have all been credited with this [8]. Only a minority of the women with eclampsia were booked patients in similar studies from other regions of the country, with the majority of patients being unbooked [2,10,12]. Recent years have seen an increase in the promotion of prevention through the identification of those who are at risk and early preeclampsia detection [10,12].…”

Section: It Is Not Entirely Apparent What Causes Seizures In Pregnantmentioning

confidence: 99%

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Eclampsia Managed at Nnamdi Azikiwe University Teaching Hospital (NAUTH), NNEWI, South-East Nigeria: A 5-Year Retrospective Cross-Sectional Studya

2023

Gynecol Obstet Open Acc

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Background: Obstetric emergencies like eclampsia continue to be a leading cause of morbidity and mortality in pregnant women and fetuses in modern society. Given its detrimental consequences on the pregnant woman, her unborn child, and any later medical difficulties linked to this illness, it has remained to be a cause of concern for obstetricians, especially in low-and middle-income countries. Hence the requirement for periodic review in our environment. Objectives: The objective of this study is to determine the prevalence, pattern of presentation as well as fetal and maternal outcome of cases of eclampsia with a view to suggest interventions to reduce the incidence and associated morbidity and mortality associated with eclampsia. Materials and Methods:This study examines all eclampsia cases treated at

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Section: It Is Not Entirely Apparent What Causes Seizures In Pregnantsupporting

confidence: 84%

Section: It Is Not Entirely Apparent What Causes Seizures In Pregnantmentioning

confidence: 99%

Section: It Is Not Entirely Apparent What Causes Seizures In Pregnantmentioning

confidence: 99%

See 1 more Smart Citation

Eclampsia Managed at Nnamdi Azikiwe University Teaching Hospital (NAUTH), NNEWI, South-East Nigeria: A 5-Year Retrospective Cross-Sectional Studya

2023

Gynecol Obstet Open Acc

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“…Maternal deaths occurred while on admission in a finding consistent with another Nigerian study. [16] The majority of women studied were unbooked and demonstrated poor health-seeking behaviour, along with the observed late referral. This is in keeping with the National Demographic Health Survey report that a third of Nigerian pregnant women did not receive antenatal care, thus exposing them to a higher risk of maternal mortality.…”

Section: Discussionmentioning

confidence: 95%

Pattern of liver enzymes and maternal outcome in eclamptic patients admitted to the Intensive Care Unit, University College Hospital, Nigeria

Idowu,

Bello

2023

SSMJ

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Introduction: Eclampsia, a hypertensive disorder, is one of the leading causes of maternal mortality in developing countries like Nigeria. We evaluated the relationship between the pattern of liver enzymes and maternal mortality in eclamptic women. Method: A retrospective study of 55 eclamptic women admitted to the Intensive Care Unit (ICU), University College Hospital, Nigeria, was conducted. Data were obtained on their demographic, obstetric, and clinical characteristics, liver enzyme patterns, and maternal outcome. Analysis was by descriptive statistics, univariate analysis, and non-parametric tests with level of significance set at p<0.05. Results: Maternal deaths occurred in 27.3% and elevation of liver enzymes was observed more among the dead patients compared with those who survived. Alanine aminotransferase (ALT) was the most commonly elevated liver enzyme, occurring in almost all (90.9%) the patients. Maternal mortality was significantly associated with age (p=0.001), saturated oxygen levels (p=0.007), elevated alkaline phosphatase (p=0.008), alanine aminotransferase (p=0.013), aspartate aminotransferase (p=0.016), and total bilirubin (p<0.001). Conclusion: Maternal mortality due to eclampsia was clinically associated with age, elevated liver enzymes and a lower serum level of total bilirubin. Liver transaminases are therefore important prognostic indicators associated with eclampsia.

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“…Also, some studies showed that OCP consumption reduced even the risk of ovarian, endometrium, and colorectal cancer [ 8 , 9 ]. Despite the benefits of using OCPs, some evidence is that they can increase the risk of adverse outcomes, including cardiovascular disease(CVD), obesity, high blood pressure, hemorrhagic stroke, breast cancer, and cerebral vein thrombosis [ 10 – 13 ]. Also, some studies showed that the consumption of OCPs can increase oxidative stress.…”

Section: Introductionmentioning

confidence: 99%

Association between oral contraceptives with lipid profile: results from Hoveyzeh cohort study (HCS)

Hashemi,

Khezri,

Saki

et al. 2023

BMC Women's Health

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Background Oral contraceptives (OCs) affect lipid metabolism, which can cause hyperlipidemia, a risk factor for cardiovascular diseases. The study was designed to evaluate the possible changes in lipid profile due to using OCs. Methods A cross-sectional study was conducted from April 2016 to August 2018 among women from the baseline phase Hoveyzeh cohort study (HCS). Sociodemographic data, anthropometric measurements, physical activity, and biochemical blood tests were measured for every participant. Multiple logistic regression was used to adjust the potential confounders. Results Among 2272 participants, 1549 women were OC users, and 723 women were non-user OCs. The mean lipid profile levels were higher in OC users than in non-user OCs. Odds of abnormal Total cholesterol (TC) in OC users were significantly higher than those of non-users OCs [OR = 1.29 (95% CI;1.05 to 1.58)]. Also, the Odds of abnormal low-density lipoprotein (LDL) in OC users was 12% higher than in non-user OCs. However, no significant relationship between abnormal LDL with Oral Contraceptive Pills (OCPs) was observed. Conclusions The mean lipid profile was higher in OC users compared to non-user OCs. This finding highlights the need for public health strategies to prevent and detect hyperlipidemia in user OCs.

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Eclampsia: A five-year retrospective review in Sagamu, South-West Nigeria

Cited by 4 publications

References 10 publications

Eclampsia Managed at Nnamdi Azikiwe University Teaching Hospital (NAUTH), NNEWI, South-East Nigeria: A 5-Year Retrospective Cross-Sectional Studya

Eclampsia Managed at Nnamdi Azikiwe University Teaching Hospital (NAUTH), NNEWI, South-East Nigeria: A 5-Year Retrospective Cross-Sectional Studya

Pattern of liver enzymes and maternal outcome in eclamptic patients admitted to the Intensive Care Unit, University College Hospital, Nigeria

Association between oral contraceptives with lipid profile: results from Hoveyzeh cohort study (HCS)

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