Eclampsia and posterior reversible encephalopathy syndrome in a parturient complicated by SARS COVID-19 pneumonia

Shankar, Vijay; Dhar, Purnima; George, Jai; Sharma, Anil; Raj, Anupam

doi:10.1016/j.bjane.2021.06.008

Cited by 7 publications

(26 citation statements)

References 4 publications

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“… 22 Only one case repeated the brain MRI, which revealed a complete reversion of the lesions. 21 None of these three cases were diagnosed with preeclampsia. The only woman diagnosed with delirium was also diagnosed with preeclampsia and presented a normal brain CT scan.…”

Section: Resultsmentioning

confidence: 92%

“…Finally, we reviewed 18 case reports from the selected 17 papers (Tables 1 and 2 ). 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 …”

Section: Resultsmentioning

confidence: 99%

“…Central nervous system involvement was reported in nine cases 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 (Table 1 ): delirium 20 ( n = 1); posterior reversible encephalopathy syndrome 21 , 22 , 23 , 24 (PRES) ( n = 4); cerebrovascular disease 25 , 26 (CVD) ( n = 2), one case of arterial involvement and one of venous; acute cerebral demyelinating disease 27 (ADEM) ( n = 1); and acute necrotizing encephalopathy 28 (ANE) ( n = 1).…”

Section: Resultsmentioning

confidence: 99%

“…Among the five cases presenting with encephalopathy (delirium and PRES), four patients presented with altered behavior and mental status or impaired consciousness 20 , 21 , 22 , 24 ; three with headache 20 , 21 , 24 ; three with generalized seizures 21 , 23 , 24 ; and one patient with bilateral blindness. 23 All these findings indicate diffuse brain injury, and one case also presented with signs of focal brain deficit: hemiparesis and aphasia.…”

Section: Resultsmentioning

confidence: 99%

“… 15 One of the reported cases of pregnant women with COVID‐19 presented with delirium with no evident brain injury. 20 There were also four cases of PRES, 21 , 22 , 23 , 24 and only one of these women presented no abnormalities in the brain image. 23 …”

Section: Discussionmentioning

confidence: 96%

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Pregnancy and neurologic complications of COVID‐19: A scoping review

Magalhães

Rocha-Filho

2022

Acta Neuro Scandinavica

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While neurologic complications are frequently reported among patients with COVID‐19 in the general population, they are unknown in pregnant women. This paper summarizes the case reports of pregnant women with confirmed SARS‐CoV‐2 infection plus a specified neurologic diagnosis. Until November 2021, 18 case reports were found. Both the central and peripheral nervous systems were equally affected: delirium ( n = 1), posterior reversible encephalopathy syndrome ( n = 4), cerebrovascular disease ( n = 2), acute cerebral demyelinating disease ( n = 1), acute necrotizing encephalopathy ( n = 1), Guillain–Barré syndrome ( n = 5), including one patient who also had vestibular neuritis, Bell's palsy ( n = 3), and rhabdomyolysis ( n = 1). The median maternal age was 32.5 (25—35) years, the median gestational age was 34 (30—36.5) weeks, and 38.9% presented previous medical conditions. Respiratory symptoms were reported in 76.5%, and 76.5% received immunotherapies to treat the COVID‐19 or the neurologic complications. Half the women required admission to ICU and, more often, were those with central nervous system involvement (77.8% vs. 22.2%; Chi‐square test, p = .018). For 64.7% of women, the most common method of delivery was surgical, although just one case was due to the neurologic complication. There were reports of one spontaneous abortion, two fetal deaths, and no maternal deaths. Only one case presented a poor neurologic outcome. It is possible that our findings are underestimated, considering that there are thousands of reports regarding neurologic complications in the general population with COVID‐19.

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Section: Resultsmentioning

confidence: 92%

“…Finally, we reviewed 18 case reports from the selected 17 papers (Tables 1 and 2 ). 19 , 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 …”

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 96%

See 3 more Smart Citations

Pregnancy and neurologic complications of COVID‐19: A scoping review

Magalhães

Rocha-Filho

2022

Acta Neuro Scandinavica

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Posterior reversible encephalopathy syndrome and reversible cerebral vasoconstriction syndrome in patients with COVID-19 infection: is there a link? A systematic review and case report analysis

et al. 2023

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During the SARS-CoV2 pandemic, several cases of Posterior Reversible Encephalopathy Syndrome (PRES) and of Reversible Cerebral Vasoconstriction Syndrome (RCVS) in COVID-19 patients have been reported, but the link between these syndromes and COVID-19 is unclear. We performed a systematic review, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement to evaluate whether SARS-CoV2 infection or the drugs used to treat it could be deemed potential risk factors for PRES or RCVS. We performed a literature search. We found 70 articles (60 on PRES and 10 on RCVS) concerning n = 105 patients (n = 85 with PRES, n = 20 with RCVS). We analyzed the clinical characteristics of the two populations separately, then performed an inferential analysis to search for other independent risk factors. We found fewer than usual PRES-related (43.9%) and RCVS-related (45%) risk factors in patients with COVID-19. Such a low incidence of risk factors for PRES and RCVS might suggest the involvement of COVID-19 as an additional risk factor for both diseases due to its capability to cause endothelial dysfunction. We discuss the putative mechanisms of endothelial damage by SARS-CoV2 and antiviral drugs which may underlie the development of PRES and RCVS.

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Die Komplexität der SARS-CoV-2-Infektion im klinischen Alltag der Geburtshilfe – Auseinandersetzung anhand eines Fallbeispiels

Möginger

Mand

Schoner

et al. 2022

Z Geburtshilfe Neonatol

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ZusammenfassungSeit Beginn der Pandemie dominiert die Sars-CoV-2-Infektion den klinischen Alltag. In der Behandlung von Hochrisikopopulationen bestand lange Unklarheit über das Ausmaß und die Konsequenzen der Infektion. Zu diesem Risikokollektiv gehört auch die schwangere Patientin. Die Etablierung von klinischen Registerstudien konnte innerhalb kürzester Zeit und unter enormer Anstrengung zu einer Einschätzung der pandemischen Lage für dieses Kollektiv beitragen. Anhand eines klinischen Falls wird im folgenden Bericht die Assoziation zwischen Sars-CoV-2 Infektion einer schwangeren Patientin mit klinischen Zeichen der Präeklampsie bis hin zur Ausbildung eines posterioren reversiblen Enzephalopathiesyndroms (PRES) beschrieben. Anhand des Falles wird die differentialdiagnostische Abklärung zwischen fulminanten Verlauf der Infektion und Präeklampsie dargelegt. Der Artikel stellt die aktuelle Datenlage zum Auftreten eines PRES in der Schwangerschaft im Zusammenhang mit einer Sars-CoV-2-Infektion dar und setzt sich mit möglichen Differentialdiagnosen auseinander. Durch die interdisziplinäre Betreuung der Patientin kann eine Übersicht zu den Aspekten des jeweiligen Fachgebietes dargelegt werden.

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Eclampsia and posterior reversible encephalopathy syndrome in a parturient complicated by SARS COVID-19 pneumonia

Cited by 7 publications

References 4 publications

Pregnancy and neurologic complications of COVID‐19: A scoping review

Pregnancy and neurologic complications of COVID‐19: A scoping review

Posterior reversible encephalopathy syndrome and reversible cerebral vasoconstriction syndrome in patients with COVID-19 infection: is there a link? A systematic review and case report analysis

Die Komplexität der SARS-CoV-2-Infektion im klinischen Alltag der Geburtshilfe – Auseinandersetzung anhand eines Fallbeispiels

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