Increasing the range of electric vehicles (EVs) is possible with the help of eco-driving techniques, which are algorithms that consider internal and external factors, like performance limits and environmental conditions, such as weather. However, these constraints must include critical variables in energy consumption, such as driver preferences and external vehicle conditions. In this article, a reasonable energy-efficient non-linear model predictive control (NMPC) is built for an electric two-wheeler vehicle, considering the Paris-Brussels route with different driving profiles and driver preferences. Here, NMPC is successfully implemented in a test bed, showing how to obtain the different parameters of the optimization problem and the estimation of the energy for the closed-loop system from a practical point of view. The efficiency of the brushless DC motor (BLCD) is also included for this test bed. In addition, this document shows that the proposal increases the chance of traveling the given route with a distance accuracy of approximately 1.5% while simultaneously boosting the vehicle autonomy by almost 20%. The practical result indicates that the strategy based on an NMPC algorithm can significantly boost the driver’s chance of completing the journey. If the vehicle energy is insufficient to succeed in the trip, the algorithm can guide the minimal State of Charge (SOC) required to complete the journey to reduce the driver energy-related uncertainty to a minimum.