Ecofriendly extraction of bioactive fractions from Sargassum muticum

Casas, María P.; Conde, Enma; Domı́nguez, Herminia; Moure, Andrés

doi:10.1016/j.procbio.2018.12.021

Cited by 29 publications

(7 citation statements)

References 38 publications

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“…However, above a certain enzyme loading, excess enzymes reduced the extraction efficiency. This finding is similar to that of bioactive compound extraction from the brown seawweed Sargassum muticum [45], protein extraction from the seaweed Gelidiella acerosa [46], phenolic extraction from cauliflower [44] and Trapa quadrispinosa [47], and polysaccharide extractions from Tuber aestivum [41]. This lower activity might be due to enzyme aggregation at high concentrations [28].…”

Section: Combined Effect Of Extraction Factorssupporting

confidence: 81%

Enzyme-Assisted Coextraction of Phenolics and Polysaccharides from Padina gymnospora

Nguyen,

Ngo,

Tran

et al. 2024

Marine Drugs

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Brown seaweed is a promising source of polysaccharides and phenolics with industrial utility. This work reports the development of a green enzyme-assisted extraction method for simultaneously extracting polysaccharides and phenolics from the brown seaweed Padina gymnospora. Different enzymes (Cellulast, Pectinex, and Alcalase), individually and in combination, were investigated, with Alcalase alone showing the highest efficiency for the simultaneous extraction of polysaccharides and phenolics. Yields from Alcalase-assisted aqueous extraction were higher than those obtained using either water alone or conventional ethanol extraction. Alcalase-assisted extraction was subsequently optimized using a response surface methodology to maximize compound recovery. Maximal polysaccharide and phenolic recovery was obtained under the following extraction conditions: a water-to-sample ratio of 61.31 mL/g, enzyme loading of 0.32%, temperature of 60.5 °C, and extraction time of 1.95 h. The extract was then fractionated to obtain alginate-, fucoidan-, and phenolic-rich fractions. Fractions exhibited potent 2,2-diphenyl-1-picrylhydrazyl radical scavenging activity with IC50 values of 140.55 µg/mL, 126.21 µg/mL, and 48.17 µg/mL, respectively, which were higher than those obtained from conventional extraction methods. The current work shows that bioactive polysaccharides and phenolics can be obtained together in high yield through a single aqueous-only green and efficient Alcalase-assisted extraction.

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Section: Combined Effect Of Extraction Factorssupporting

confidence: 81%

Enzyme-Assisted Coextraction of Phenolics and Polysaccharides from Padina gymnospora

Nguyen,

Ngo,

Tran

et al. 2024

Marine Drugs

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“…Finally, some authors have reported the presence of phenolic compounds in S. muticum , including (ordered from highest to lowest concentration): hydroxybenzoic and gallic acids, p -hydroxybenzaldehyde, vanillic acid, 3,4-dihydroxybenzaldehyde and protocatechuic, ferulic, p -coumaric, caffeic, syringic, and chlorogenic acids [ 107 ]. Several bioactivities of S. muticum , such as antioxidant, antimicrobial, anticancer, or anti-inflammatory, have been attributed to the presence of phenolic compounds with high antioxidant capacity, particularly to phlorotannins (e.g., phloroglucinol, diphlorethol, bifuhalol), which are exclusively found in marine seaweed [ 78 , 108 , 109 , 110 , 111 ].…”

Section: Main Invasive Species Of Northwest Spain and Their Bioactive Compoundsmentioning

confidence: 99%

The Use of Invasive Algae Species as a Source of Secondary Metabolites and Biological Activities: Spain as Case-Study

et al. 2021

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In the recent decades, algae have proven to be a source of different bioactive compounds with biological activities, which has increased the potential application of these organisms in food, cosmetic, pharmaceutical, animal feed, and other industrial sectors. On the other hand, there is a growing interest in developing effective strategies for control and/or eradication of invasive algae since they have a negative impact on marine ecosystems and in the economy of the affected zones. However, the application of control measures is usually time and resource-consuming and not profitable. Considering this context, the valorization of invasive algae species as a source of bioactive compounds for industrial applications could be a suitable strategy to reduce their population, obtaining both environmental and economic benefits. To carry out this practice, it is necessary to evaluate the chemical and the nutritional composition of the algae as well as the most efficient methods of extracting the compounds of interest. In the case of northwest Spain, five algae species are considered invasive: Asparagopsis armata, Codium fragile, Gracilaria vermiculophylla, Sargassum muticum, and Grateulopia turuturu. This review presents a brief description of their main bioactive compounds, biological activities, and extraction systems employed for their recovery. In addition, evidence of their beneficial properties and the possibility of use them as supplement in diets of aquaculture animals was collected to illustrate one of their possible applications.

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“…A study used an EAE coupled with UAE to achieve the eco-friendly extraction of soluble bioactive fractions from the macroalga S. muticum . Using a mixture of commercial complex enzyme formulations, these authors obtained an S. muticum extract rich in bioactive components such as carbohydrates, monosaccharides, oligosacaccharides and polyphenols [ 194 ]. A similar strategy was used by other authors [ 195 ] to extract bioactive compounds from green and brown seaweed C. tomentosum , S. muticum and O. pinnatifida.…”

Section: Novel Liquid–liquid and Solid–liquid Extraction Technologmentioning

confidence: 99%

Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications

et al. 2020

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In the last few decades, attention on new natural antimicrobial compounds has arisen due to a change in consumer preferences and the increase in the number of resistant microorganisms. Macroalgae play a special role in the pursuit of new active molecules as they have been traditionally consumed and are known for their chemical and nutritional composition and their biological properties, including antimicrobial activity. Among the bioactive molecules of algae, proteins and peptides, polysaccharides, polyphenols, polyunsaturated fatty acids and pigments can be highlighted. However, for the complete obtaining and incorporation of these molecules, it is essential to achieve easy, profitable and sustainable recovery of these compounds. For this purpose, novel liquid–liquid and solid–liquid extraction techniques have been studied, such as supercritical, ultrasound, microwave, enzymatic, high pressure, accelerated solvent and intensity pulsed electric fields extraction techniques. Moreover, different applications have been proposed for these compounds, such as preservatives in the food or cosmetic industries, as antibiotics in the pharmaceutical industry, as antibiofilm, antifouling, coating in active packaging, prebiotics or in nanoparticles. This review presents the main antimicrobial potential of macroalgae, their specific bioactive compounds and novel green extraction technologies to efficiently extract them, with emphasis on the antibacterial and antifungal data and their applications.

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Ecofriendly extraction of bioactive fractions from Sargassum muticum

Cited by 29 publications

References 38 publications

Enzyme-Assisted Coextraction of Phenolics and Polysaccharides from Padina gymnospora

Enzyme-Assisted Coextraction of Phenolics and Polysaccharides from Padina gymnospora

The Use of Invasive Algae Species as a Source of Secondary Metabolites and Biological Activities: Spain as Case-Study

Macroalgae as a Source of Valuable Antimicrobial Compounds: Extraction and Applications

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