Background and targets: In 2016, 40.5 million (71%) of the 56.9 million deaths worldwide were due to NCDs [1]. In the Caribbean, NCDs in 2010 outpaced those in North and South America [2]. Male death rate from NCDs is higher than female death rate [1,2]. This fact served as the basis for comparative studies on nutritional risk factors for NCDs in men in the Caribbean (CC) and Mediterranean (MC) countries. MC are a globally recognized reference for good nutrition and low incidence of NCDs [3].The impact of nutritional patterns on the burden of melanoma, multiple sclerosis, hypertensive heart disease and diabetes mellitus in men in the Mediterranean (MC) and Caribbean (CC) countries was researched.Methods: Data on the NCD (DALY) burden in men in MC and CC were obtained from [GBD 2004]. Information on food consumption levels in countries was obtained from FAO [FAO-HQfao.org] for 2003-05. U-Manna-Whitney and multiple linear regression analysis were used to analyze differences in nutrition structure and NCD burden in MC and CC. Using the U-Manna-Whitney Criterion, we evaluated the incidence of the most important NCDs in MC and CC. Regression analysis evaluated the impact of risk factors (independent variables) on DALY for 4 types of NCDs (dependent variables). The independent variables in the first stage of the analysis were 4 food structure fractions: animal products (AP); vegetables (CV); fruits (FS); and alcoholic beverages (AB). Dependent variables were the burden of melanoma, multiple sclerosis, hypertensive heart disease, and diabetes mellitus as the diseases with the highest frequency of 63 NCDs in MC and CC. In the second stage of regression analysis, predictions of the effect of increase on the of risk factors (independent variables) on DALY for 4 types of NCDs (dependent variables) were evaluated.
Results:The total NCD burden in MC was 1.3 times lower than in CC (p = 0.006). Total daily food consumption (TDC) as well as animal products fraction (AP) in MC was 1.5 times higher than in CC (p = 0.0002). The share of CV (vegetables) in MC was 1.9 times higher than in CC (p = 0.001). The share of FS (fruits) in MC was 1.2 times higher than in CC (p = 0.3). The share of AB (alcohol) in MC was 2.5 times higher than in CC (p = 0.009).The burden of melanoma and multiple sclerosis in MC was 2 times higher than in CC (p = 0.002). In CC the burden of diabetes and hypertensive heart disease was 2.5 times higher (p = 0.001). In MC, there were 1.5-2 times higher than in CC: BMI (p = 0.03), blood cholesterol (p = 0.0002), and blood pressure (p = 0.002).As a result of multiple regression analysis, it was found that the nutrition structure fractions AP and AB, as well as GDP have the largest influence on the