In recent years, ecological teaching of college English has become a research focus. This research mainly discusses the ecological teaching mode of college English based on the computer network environment. The college English classroom teaching and the network autonomous learning classroom under the computer network environment of the university public foreign language teaching and research department are selected as the objective test environment, and the qualitative and quantitative integration are combined to summarize the imbalanced performance in the integration. From a micro point of view, deeply explore the constraints that affect the successful construction of an ecological teaching model in a computer network environment, focus on investigating the “student anxiety” in the network teaching environment, sort out the original text data obtained from the experiment, and conduct scientific statistics on the effective data, quantitative analysis, find out the cause of anxiety, thus complete the experimental design and data collection. On average, 55.6% of students have an anxiety tendency when they study online, and even 35.9% of students have serious anxiety and frustration. This research has guiding significance for the ecological teaching of college English.