The field experiment was conducted at Vegetable Research Farm, Kalyanpur of Chandra Shekhar Azad University of Agriculture and Technology, Kanpur, India during two consecutive rabi seasons of 2019-20 and 2020-21, to find out the effect of PGRs and their spray schedules on tomato. The experiment was laid out in Factorial Randomized Block Design (FRBD) with 27 treatment combinations and replicated thrice under insect proof net house. The experiment comprised nine levels of plant growth regulators viz., GA3 @ 50 ppm, GA3 @ 75 ppm, GA3 @ 100 ppm, NAA @ 20 ppm, NAA @ 30 ppm, NAA @ 40 ppm, 4-CPA @ 20 ppm, 4-CPA @ 30 ppm and 4-CPA @ 40 ppm and three spray schedules viz., at 30 and 45 DAT, at 30, 45 and 60 DAT and at 30, 45, 60 and 75 DAT. The tomato hybrid ‘NS- 4266’ was used in experiment. Results of the experiment revealed that the application of GA3 @ 75 ppm recorded significantly highest plant height (327.277 and 315.377 cm), stem girth (3.233 and 3.207 cm), internodal length (17.164 and 18.153 cm) and fruit yield per plant (12.223 and 13.208 kg) during both the years. The significantly earliest flowering (31.094 and 31.536 days), fruiting (40.352 and 40.307 days) and first harvest/picking (105.204 and 104.517) were also observed with this treatment. In case of spray schedules, the plants were sprayed at 30, 45, 60 and 75 days after transplanting (four sprays) recorded significantly highest values of all the growth parameters and fruit yield. The earliest flowering, fruiting and harvesting were also observed with four sprays schedule. Based on two years study, the significantly highest growth parameters, fruit yield and earliness in flowering, fruiting and harvesting were found with the treatment of application of GA3 @ 75 ppm and spray schedule of 30, 45, 60 and 75 days after transplanting. Hence, it may be recommended for higher productivity from tomato crop under protected conditions.