Economic Analysis of Outpatient Parenteral Antimicrobial Therapy (Opat): A Systematic Review

Psaltikidis, EM; Silva, E; Bustorff‐Silva, Joaquim Murray; Moretti, M.L.; Resende,

doi:10.1016/j.jval.2015.09.1950

Cited by 5 publications

(2 citation statements)

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“…This resource saving can reach 40,000 dollars per patient. 28 , 29 , 30 , 31 , 32 In Brazil, implementation of an OPAT program in a public orthopedics and trauma hospital was shown to enable reallocation of over 11,000 hospital beds for patients who required hospitalization. 5 …”

Section: Protocols For Antimicrobial Use and Monitoringmentioning

confidence: 99%

Recommendations for outpatient parenteral antimicrobial therapy in Brazil

Oliveira

Carvalho

Cimerman

et al. 2017

The Brazilian Journal of Infectious Diseases

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A panel of national experts was convened by the Brazilian Infectious Diseases Society in order to determine the recommendations for outpatient parenteral antimicrobial therapy (OPAT) in Brazil. The following aspects are covered in the document: organization of OPAT programs; patient evaluation and eligibility criteria, including clinical and sociocultural factors; diagnosis of eligibility; venous access and antimicrobial infusion devices; protocols for antimicrobial use and monitoring and cost-effectiveness.

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Section: Protocols For Antimicrobial Use and Monitoringmentioning

confidence: 99%

Recommendations for outpatient parenteral antimicrobial therapy in Brazil

Oliveira

Carvalho

Cimerman

et al. 2017

The Brazilian Journal of Infectious Diseases

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“…The expansion of OPAT worldwide has been driven by factors including: a drive for more cost-effective use of resources; reduced risks of healthcare acquired infection; alignment with the philosophy of patient driven care; an aim to achieve high levels of patient acceptability and satisfaction; and improved quality of life. Evidence of these outcomes has been derived from a systematic review of the cost effectiveness of OPAT highlighting that OPAT is cost-effective without increasing patient complications 3. A narrative review of studies concluded that patients prefer home administration allowing continuation of daily activities 2.…”

Section: Introductionmentioning

confidence: 99%

Home self-administration of intravenous antibiotics as part of an outpatient parenteral antibiotic therapy service: a qualitative study of the perspectives of patients who do not self-administer

et al. 2019

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ObjectivesThis study aimed to use a theoretical approach to understand the determinants of behaviour in patients not home self-administering intravenous antibiotics.SettingOutpatient care: included patients were attending an outpatient clinic for intravenous antibiotic administration in the northeast of Scotland.ParticipantsPatients were included if they had received more than 7 days of intravenous antibiotics and were aged 16 years and over. Twenty potential participants were approached, and all agreed to be interviewed. 13 were male with a mean age of 54 years (SD +17.6).OutcomesKey behavioural determinants that influenced patients’ behaviours relating to self-administration of intravenous antibiotics.DesignQualitative, semistructured in-depth interviews were undertaken with a purposive sample of patients. An interview schedule, underpinned by the Theoretical Domains Framework (TDF), was developed, reviewed for credibility and piloted. Interviews were audio-recorded and transcribed verbatim. Data were analysed thematically using the TDF as the coding framework.ResultsThe key behavioural determinants emerging as encouraging patients to self-administer intravenous antibiotics were the perceptions of being sufficiently knowledgeable, skilful and competent and that self-administration afforded the potential to work while administering treatment. The key determinants that impacted their decision not to self-administer were lack of knowledge of available options, a perception that hospital staff are better trained and anxieties of potential complications.ConclusionThough patients are appreciative of the skills and knowledge of hospital staff, there is also a willingness among patients to home self-administer antibiotics. However, the main barrier emerges to be a perceived lack of knowledge of ways of doing this at home. To overcome this, a number of interventions are suggested based on evidence-based behavioural change techniques.

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