Economic and Behavioral Influencers of Vaccination and Antimicrobial Use

Wagner, Caroline E.; Prentice, Joseph A.; Saad-Roy, Chadi M.; Yang, Luojun; Grenfell, Bryan T.; Levin, Simon A.; Laxminarayan, Ramanan

doi:10.3389/fpubh.2020.614113

Cited by 43 publications

(38 citation statements)

References 175 publications

(222 reference statements)

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“…Limited economic resources are associated with conflicting life priorities that prevent individuals from prioritizing vaccination. Workers outside the home who have not yet been infected may have developed a perception of low risk from COVID-19 14,17,35,36 .…”

Section: Discussionmentioning

confidence: 99%

COVID-19 vaccine acceptance among adults in four major US metropolitan areas and nationwide

El-Mohandes

White

Wyka

et al. 2021

Sci Rep

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This study assesses attitudes towards COVID-19 vaccination and the predictive value of COVID-VAC, a novel scale, among adults in the four largest US metropolitan areas and nationally. A 36-item survey of 6037 Americans was conducted in mid-April 2021. The study reports factors for COVID-19 vaccine acceptance among: (1) already vaccinated; (2) unvaccinated but willing to accept a vaccine; and (3) unvaccinated and unwilling to vaccinate. More than 20% were unwilling to vaccinate, expressing concerns about vaccine efficacy and safety and questioning the disease’s severity. Poverty, working outside of the home and conservative political views are predictors of unwillingness. Conversely, those who either personally tested positive for COVID-19, or had a family member who did so, were more likely to accept vaccination. Majorities of all respondents supported vaccination mandates for employees and university students. Respondents preferred to receive vaccines in their doctor´s office. Lower income and conservative ideology, but not race, were strongly associated with vaccine unwillingness. The predictive value of COVID-VAC was demonstrated. While vaccination mandates are likely to be accepted, additional effective, targeted interventions to increase vaccine uptake are needed urgently.

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Section: Discussionmentioning

confidence: 99%

COVID-19 vaccine acceptance among adults in four major US metropolitan areas and nationwide

El-Mohandes

White

Wyka

et al. 2021

Sci Rep

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“…S13 for other parameter choices). Vaccine refusal ( 23 ) may also affect the attainment of community immunity through vaccinal immunity in the longer term (see supplementary materials).…”

Section: Epidemiological Impactsmentioning

confidence: 99%

Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes

Saad-Roy

Morris

Metcalf

et al. 2021

Science

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220

224

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In the face of vaccine dose shortages and logistical challenges, various deployment strategies are being proposed to increase population immunity levels to SARS-CoV-2. Two critical issues arise: how will the timing of delivery of the second dose affect both infection dynamics and prospects for the evolution of viral immune escape via a build-up of partially immune individuals. Both hinge on the robustness of the immune response elicited by a single dose, compared to natural and two-dose immunity. Building on an existing immuno-epidemiological model, we find that in the short-term, focusing on one dose generally decreases infections, but longer-term outcomes depend on this relative immune robustness. We then explore three scenarios of selection and find that a one-dose policy may increase the potential for antigenic evolution under certain conditions of partial population immunity. We highlight the critical need to test viral loads and quantify immune responses after one vaccine dose, and to ramp up vaccination efforts throughout the world.

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“…This is a more context-specific model that acknowledged the importance of context, society and individual and group differences in the success of a vaccination program. Studies on vaccine hesitancy have shown the significance of context-specific factors such as risk perception, social norms, group dynamics and political ideology as important determinants of vaccine hesitancy and refusal [ 39 , 40 ]. A recent study in Malaysia by Syed Alwi et al .…”

Section: Introductionmentioning

confidence: 99%

The lived experiences of a COVID-19 immunization programme: vaccine hesitancy and vaccine refusal

et al. 2022

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Background The COVID-19 pandemic has resulted in a global health emergency and lock-down measures to curb the uncontrolled transmission chain. Vaccination is an effective measure against COVID-19 infections. In Malaysia amidst the national immunisation programme (NIP) which started in February 2021, there were rising concerns regarding the prevalence of vaccine hesitancy and refusal, and therefore, vaccine uptake among Malaysians. Although there are many quantitative studies on COVID-19 vaccination, the subjective experience of individuals was understudied. This study aims to explore the lived experiences of Malaysians regarding vaccine hesitancy and refusal, and facilitating factors that could enhance vaccine acceptance and uptake. Methods This qualitative study employed the hermeneutic phenomenological study design. Purposive sampling strategies were used to recruit Malaysians that had direct experiences with friends, family members and their community who were hesitating or refusing to accept the COVID-19 vaccines. A semi-structured interview guide was developed based on the expert knowledge of the investigators and existing literature on the topic. A series of focus group interviews (FGIs) was conducted online facilitated by a multidisciplinary team of experts. The group interviews were transcribed verbatim and analysed. Results Fifty-nine participants took part in seven FGIs. We found that “incongruence” was the overall thematic meaning that connected all the 3 main themes. These themes comprise firstly, the incongruence between the aims and implementation of the National Immunization Program which highlighted the gap between realities and needs on the ground. Secondly, the incongruence between Trust and Mistrust revealed a trust deficit in the government, COVID-19 news, and younger people’s preference to follow the examples of local vaccination “heroes”. Thirdly, the incongruence in communication showed the populace’s mixed views regarding official media and local social media. Conclusions This study provided rich details on the complex picture of the COVID-19 immunization program in Malaysia and its impact on vaccine hesitancy and refusal. The inter-related and incongruent factors explained the operational difficulty and complexity of the NIP and the design of an effective health communication campaign. Identified gaps such as logistical implementation and communication strategies should be noted by policymakers in implementing mitigation plans.

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Economic and Behavioral Influencers of Vaccination and Antimicrobial Use

Cited by 43 publications

References 175 publications

COVID-19 vaccine acceptance among adults in four major US metropolitan areas and nationwide

COVID-19 vaccine acceptance among adults in four major US metropolitan areas and nationwide

Epidemiological and evolutionary considerations of SARS-CoV-2 vaccine dosing regimes

The lived experiences of a COVID-19 immunization programme: vaccine hesitancy and vaccine refusal

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