Economic and Technical Feasibility of Betanin and Pectin Extraction from <i>Opuntia ficus-indica</i> Peel via Microwave-Assisted Hydrodiffusion

Ciriminna, Rosaria; Fidalgo, Alexandra; Avellone, Giuseppe; Carnaroglio, Diego; Danzì, Carmelo; Timpanaro, Giuseppe; Meneguzzo, Francesco; Ilharco, Laura M.; Pagliaro, Mario

doi:10.1021/acsomega.9b00960

Cited by 14 publications

(5 citation statements)

References 25 publications

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“…However, currently, there is little or no available literature on the disintegrating properties of pectin. It has been reported that sourcing pectins from plants with short maturity and investigating their disintegrating and other tablet formulation properties will diversify their use in the pharmaceutical industry and attract huge revenues for pharmaceutical industries involved in this research [ 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

Potential and Comparative Tablet Disintegrant Properties of Pectin Obtained from Five Okra Genotypes in Ghana

et al. 2021

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Okra pectin has been studied as a potential excipient in tablet formulations for pharmaceutical industries. Okra is widely grown and available in Ghana and other parts of the world. The prospective use of pectin from okra genotypes grown in Ghana as tablet disintegrants has not been reported. This study aims to determine the potential and comparative disintegrating properties of pectin from five okra genotypes (Abelmoschus esculentus L.) in Ghana using uncoated immediate release paracetamol tablet formulations. The yield of the pectin from the various genotypes ranged between 6.12 and 18.84% w/w. The extracted pectins had pH ranging from slightly acidic to almost neutral (6.39–6.92). Pectin from the various genotypes exhibited good swelling indexes (˃200%), varying solubility in different solvents, and low moisture content (˂20%). Elemental analysis of the extracted pectin from the various genotypes revealed very low levels of toxic metals and micronutrients. Pectin from the various genotypes was evaluated as disintegrants within concentrations of 5–10% w/w (F1–F18). Their disintegrating properties were compared to that of maize starch BP. All the formulated batches of uncoated immediate release paracetamol tablets (F1–F18) passed the following: uniformity of weight test, uniformity of dimensions, hardness, friability (˂1%), and drug content (95–105%). Significant differences ( p ≤ 0.05 ) were observed between the hardness of the maize starch tablets and tablets formulated from pectin of the various genotypes. Pectin from all genotypes other than PC5 exhibited good disintegrating properties (DT ˂ 15 min) and subsequently passed the dissolution profile test (≥70% release in 45 minutes). Tablets formulated with PC5 as disintegrants at all concentrations (5% w/w (F5), 7.5% w/w (F11), and 10% w/w (F17)) failed the disintegration and dissolution tests. Ultimately, pectins extracted from PC1, PC2, PC3, and PC4 can be commercially exploited as disintegrants in immediate release tablets.

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Section: Introductionmentioning

confidence: 99%

Potential and Comparative Tablet Disintegrant Properties of Pectin Obtained from Five Okra Genotypes in Ghana

et al. 2021

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“…Furthermore, using agricultural waste, durian peel, can reduce waste disposal and burning that causes several environmental pollutants and, at the same time, improve the economic value of durian peels [2]. The world's market demand for pectin has been growing quickly (> 7 % annual growth rate) due to the expanding consumer base for low-calorie and lowfat food products [41]. Moreover, the market size of pectin is expected to expand more rapidly than gelatin and starch [42].…”

Section: Economic and Environmental Benefits Of Extracting Pectin Fro...mentioning

confidence: 99%

Pectin from Durian (Durio zibethinus Murray) Peel: Microwave-Assisted Extraction Followed by Solvent Extraction

Kheowmung

2024

Trends Sci

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The world market demand for pectin has been growing fast due to the expanding consumer base for low-calorie and low-fat food products. Thus, there was a need to explore other sources of pectin. This study extracted pectin from durian (Durio zibethinus Murray) peel cv. Long lab-lae. Before solvent extraction, microwave-assisted extraction was utilized to improve the pectin yield. The parameters during the pectin extraction process were investigated using acetic acid concentrations ranging from 10 to 40 % at pH 2, extraction temperatures ranging from 40 to 100 °C, and extraction times ranging from 2 to 6 h. The pectin extraction was carried out at pH 2.0 because a higher pH significantly reduced the yield. The results showed the parameters had a significant influence on the yield. It decreased at a higher acid concentration, extraction temperature and extraction time. It was noticed that the pectin turned into liquid at a higher temperature, 100 °C. Therefore, the optimum conditions for extracting the highest yield of pectin were 20 % acetic acid, an extraction temperature of 80 °C, and an extraction time of 2 h. The pectin yield under these optimum conditions was 1.91 %. The Fourier transform infrared spectroscopy (FT-IR) analysis confirmed the presence of functional groups in the fingerprint region of identification for polysaccharides in the extracted pectin. The FT-IR spectrum of the pectin in durian peel was extremely close to that of commercial pectin. There was limited published data on extracting and characterizing pectin from durian peel. Thus, this study could pave the way for using durian peel pectin, for instance, in food processing (i.e., gelling agent for weak-acid, low-calorie food) and pharmaceutical applications. Furthermore, using durian peel, which is agricultural waste, reduces the disposal and burning of waste to the environment, causing several pollutions and improving the economic value of durian peel. HIGHLIGHTS Acetic acid concentration, extraction temperature and time impacted durian peel pectin yield Durian peel pectin yield was decreased at a higher acetic concentration, extraction temperature and time The optimum extraction conditions were 20 % acetic acid, 80 °C and 2 h FT-IR spectrum of the durian peel pectin was extremely close to that of commercial pectin GRAPHICAL ABSTRACT

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“…OFI peels are rich in proteins, vitamins, minerals, and carbohydrates (dietary fiber and pectin) as well as bioactive substances known for their source of beneficial properties. Numerous studies have been published that found that OFI peels have multiple physiological activities such as antioxidant, antiinflammatory, antimicrobial, and anti-acetylcholinesterase [4,[6][7][8].…”

Section: Introductionmentioning

confidence: 99%

Opuntia Ficus-Indica Peel By-Product as a Natural Antioxidant Food Additive and Natural Anticoccidial Drug

Amrane-Abider,

Imre,

Herman

et al. 2023

Foods

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The present study was carried out to valorize the Opuntia ficus-indica (OFI) by-products by extracting and identifying their biochemical compounds and evaluating their antioxidant potential by in vitro activities (DPPH radical and FRAP), as well as their capacity to stabilize margarine oxidation (rancimat test). In addition, their in vitro anticoccidial effect on the destruction of Eimeria oocysts isolated from naturally infected chickens was also targeted. Microwaves and response surface methodology tools were used to extract the maximum amount of phenolic compounds (42.05 ± 0.46 GAE mg/g DW of total phenolic compounds in 90 s at 400 watts). Moreover, the effect of extraction factors was also studied. Eight phenolic compounds, including isorhamnetin, dihydrokaempferol, and kaempferol-3-O-rutinoside, were identified. The findings confirmed that OFI peel extract has strong antioxidant activities (DPPH radical, ferric reducing power). The rancimat test shows that OFI peel extract improves margarine stability by 3.2 h. Moreover, it has a notable destruction rate of Eimeria oocysts (30.06 ± 0.51%, LC50: 60.53 ± 0.38 mg/mL). The present investigation offers promise for the reuse of food waste as natural margarine additives, protection of the environment, and substitution of anticoccidial synthetic treatments.

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Economic and Technical Feasibility of Betanin and Pectin Extraction from Opuntia ficus-indica Peel via Microwave-Assisted Hydrodiffusion

Cited by 14 publications

References 25 publications

Potential and Comparative Tablet Disintegrant Properties of Pectin Obtained from Five Okra Genotypes in Ghana

Potential and Comparative Tablet Disintegrant Properties of Pectin Obtained from Five Okra Genotypes in Ghana

Pectin from Durian (Durio zibethinus Murray) Peel: Microwave-Assisted Extraction Followed by Solvent Extraction

Opuntia Ficus-Indica Peel By-Product as a Natural Antioxidant Food Additive and Natural Anticoccidial Drug

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