2022
DOI: 10.1371/journal.pone.0269703
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Economic burden of sickle cell disease in Brazil

Abstract: Background Sickle cell disease (SCD) may cause several impacts to patients and the whole society. About 4% of the population has the sickle cell trait in Brazil, and 60,000 to 100,000 have SCD. However, despite recognizing the significant burden of disease, little is known about SCD costs. Objective To estimate SCD societal costs based on disease burden modelling, under Brazilian societal perspective. Methods A disease burden model was built considering the societal perspective and a one-year time horizon,… Show more

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Cited by 10 publications
(10 citation statements)
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“…Finally, the lack of incorporating societal expenditures, such as absenteeism, job loss, and supportive care needs, was another limitation of our analyses. 31 , 45 , 46 , 47 The annual health care expenditures we reported were high, but the expenditures to society are also likely significant. For example, most Medicare-insured individuals in our study population were aged <65 years, suggesting they experience disabilities that qualify them for Medicare, which could drive expenditure disparities between super-utilizers and lower-utilizers even higher.…”
Section: Discussionmentioning
confidence: 84%
“…Finally, the lack of incorporating societal expenditures, such as absenteeism, job loss, and supportive care needs, was another limitation of our analyses. 31 , 45 , 46 , 47 The annual health care expenditures we reported were high, but the expenditures to society are also likely significant. For example, most Medicare-insured individuals in our study population were aged <65 years, suggesting they experience disabilities that qualify them for Medicare, which could drive expenditure disparities between super-utilizers and lower-utilizers even higher.…”
Section: Discussionmentioning
confidence: 84%
“… 1 , 2 The most used iron chelator in Brazil is deferasirox because it is effective, safe and can be administered orally once a day. 16 …”
Section: Discussionmentioning
confidence: 99%
“…Brazil is a country of continental dimensions with socio‐economic inequalities that are reflected in population health and in research [26]. As a consequence, a national scope is a challenge.…”
Section: Discussionmentioning
confidence: 99%