2020
DOI: 10.1136/bmjopen-2019-036047
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Economic evaluation alongside the Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial (E-PROSPECT): study protocol

Abstract: IntroductionVentilator-associated pneumonia (VAP) is a common healthcare-associated infection in the intensive care unit (ICU). Probiotics are defined as live microorganisms that may confer health benefits when ingested. Prior randomised trials suggest that probiotics may prevent infections such as VAP and Clostridioides difficile–associated diarrhoea (CDAD). PROSPECT (Probiotics to Prevent Severe Pneumonia and Endotracheal Colonization Trial) is a multicentre, double-blinded, randomised controlled trial compa… Show more

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Cited by 3 publications
(10 citation statements)
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“…Similar methodology has been described elsewhere. 15 A line-item list of unit costs and health care resource use was devised, using categories including the following: medications, personnel, diagnostic radiology and laboratory testing, operations and procedures, and per-day hospital (e.g., hoteling) costs not otherwise encompassed, in accordance with recommendations on measuring resource use. 10,[16][17][18] Total costing (resource use multiplied by unit cost) methodology is similarly described elsewhere.…”
Section: Unit Costs and Health Resource Usementioning
confidence: 99%
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“…Similar methodology has been described elsewhere. 15 A line-item list of unit costs and health care resource use was devised, using categories including the following: medications, personnel, diagnostic radiology and laboratory testing, operations and procedures, and per-day hospital (e.g., hoteling) costs not otherwise encompassed, in accordance with recommendations on measuring resource use. 10,[16][17][18] Total costing (resource use multiplied by unit cost) methodology is similarly described elsewhere.…”
Section: Unit Costs and Health Resource Usementioning
confidence: 99%
“…10,[16][17][18] Total costing (resource use multiplied by unit cost) methodology is similarly described elsewhere. 15 Duplicate disaggregate unit costs reported at a site level were removed, to avoid double-counting. 15 We preferentially recorded unit costs published by public health care payers (e.g., provincial schedule of benefits, formularies from jurisdictions) as an estimation of unit costs.…”
Section: Unit Costs and Health Resource Usementioning
confidence: 99%
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