Economic Evaluation of Text-Messaging and Smartphone-Based Interventions to Improve Medication Adherence in Adolescents with Chronic Health Conditions: A Systematic Review

Badawy, Sherif M.; Kuhns, Lisa M.

doi:10.2196/mhealth.6425

Cited by 106 publications

(78 citation statements)

References 40 publications

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“…Given the scalability of these interventions and other factors, they also have the potential to reduce health care costs . As such, a major consideration in the implementation of eHealth and mHealth interventions more generally has been the topic of cost‐effectiveness . Findings from the current review suggest that examinations of cost‐effectiveness of interventions within pediatric oncology are a ripe area of future investigation—as no data regarding cost‐effectiveness was found in the current review.…”

Section: Discussionmentioning

confidence: 89%

“…“eHealth” has been referred to as the general use of information technology in the promotion, prevention, treatment, and maintenance of health (e.g., internet, digital gaming, virtual reality, and robotics), whereas “mHealth” has been referred to as the use of mobile and wireless applications (e.g., text messaging, apps, wearable devices, remote sensing, and social media platforms) in the delivery of health‐related services . There is growing evidence to support the feasibility, acceptability, and efficacy of eHealth and mHealth interventions in improving medication adherence, self‐management, psychosocial well‐being, and health outcomes in children, adolescents, and adults with chronic health conditions, yet cost‐effectiveness remains unclear …”

Section: Introductionmentioning

confidence: 99%

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eHealth and mHealth interventions in pediatric cancer: A systematic review of interventions across the cancer continuum

et al. 2019

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Objectives: The primary objectives were to (a) identify current published research in electronic health (eHealth) and mobile health (mHealth) interventions for youth undergoing cancer treatment and child, adolescent, and young adult survivors of childhood cancer and (b) critically appraise the current scientific evidence on their effectiveness and efficacy. As an exploratory aim, we identified pediatric cancer patients' and survivors' perceptions, attitudes, and concerns related to eHealth and mHealth interventions. Methods: A comprehensive search of the literature was performed to identify peerreviewed journal articles that included the use of mHealth and eHealth interventions among youth receiving active cancer treatment and survivors of childhood cancer through the age range of childhood to young adulthood (mean age 21 years or younger at the time of diagnosis; mean age 39 years or younger at the time of intervention). The search was conducted via six electronic databases: PubMed, CINAHL, EMBASE, PsycINFO, IEEEXplore and the Cochrane Library.Results: Of the 1879 potential records examined, 21 met criteria for inclusion for a total of 1506 participants. Of the investigations included, 13 were randomized controlled trials, and eight were nonrandomized studies. Findings demonstrated feasibility as well as acceptability with these approaches. Evidence of efficacy for interventions targeting emotional distress, health behaviors, health outcomes, and neurocognitive functioning was mixed. Conclusions:Given the growing evidence of efficacy, coupled with increasing access to digital technologies, eHealth and mHealth may serve an important role in improving mental and physical health outcomes of youth undergoing cancer treatment and child, adolescent, and young adult survivors of childhood cancer. K E Y W O R D Sadolescent, cancer, childhood, eHealth, emotional distress, mHealth, neurocognitive functioning, oncology, patient-reported outcomes, young adult

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Section: Discussionmentioning

confidence: 89%

Section: Introductionmentioning

confidence: 99%

eHealth and mHealth interventions in pediatric cancer: A systematic review of interventions across the cancer continuum

et al. 2019

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“…Furthermore, although mobile phone interventions are cost‐effective, only one of the included studies (Vidmar et al, ) conducted an economic evaluation. However, the economic benefits of mobile phone interventions are not confirmed due to lack of evidence, thereby hindering the broader application (Badawy & Kuhns, ; Iribarren, Cato, Falzon, & Stone, ). Finally, participants’ privacy is another issue in mobile phone usage research, which compromises the effectiveness of the intervention (Arora, Yttri, & Nilsen, ).…”

Section: Discussionmentioning

confidence: 99%

Mobile phone interventions to improve adolescents' physical health: A systematic review and meta‐analysis

Shin

Kim

Lee

2019

Public Health Nursing

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Background We conducted a systematic review and meta‐analysis to evaluate the effectiveness of mobile phone intervention in promoting a healthy lifestyle among adolescents. Methods Six databases were used for literature searches: MEDLINE, Embase, Cochrane Library, Cumulative Index to Nursing and Allied Health Literature, KoreaMed, and Research Information Sharing Service. The keywords used were “adolescents,” “mobile phone,” “smartphone,” “mHealth,” “application,” and “text message.” The search was restricted to intervention studies using randomized controlled studies and pre‐ and post‐control group studies targeting adolescents, all written in English and Korean. Results Eleven intervention studies, including 1,472 adolescents, were included. Included studies published between 2013 and 2018 used various mobile phone features: four studies utilized phone call and text messaging, whereas seven studies used health applications. Methodological quality was assessed and the overall quality of the studies was mid to low. The pooled data favored intervention in improving physical activity and reducing sugar‐sweetened beverage intake and screen time. In a pooled data analysis, the effectiveness of mobile phone intervention on body mass index and weight loss was not statistically significant. Conclusion This study provided evidence that mobile phone intervention improved physical health and fitness among adolescents. More beneficial effects can be guaranteed when interventions involve informative and motivational messages. Strategies to ensure the durability of such interventions are needed to promote active and continuous engagement.

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“…61 In order for physician to recommend this application to patients, effectiveness evaluations for improving health and economic outcomes are necessary. 62,63…”

Section: Implications For Future Researchmentioning

confidence: 99%

Enhancing Asthma Patients' Self-Management through Smartphone-Based Application: Design, Usability Evaluation, and Educational Intervention

et al. 2019

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Objective The aim of this study was to design and evaluate a smartphone-based application for improving self-management in patients with asthma and evaluate its effects on their knowledge. Methods In this applied research, based on the Clinical Practice Guideline and a systematic review, a questionnaire was designed to determine the application information content and functionality requirements by 15 pediatric and adult asthma and allergy specialist. Then the application was designed and developed using Adobe Air software on the Android operating system. Usability evaluation of the mobile application was performed using the standard questionnaire for user interaction satisfaction (QUIS), which completed by 30 patients with asthma, 8 information technology (IT) specialists, and 2 asthma and allergy specialists. Self-management knowledge of 30 asthma patients was measured using a researcher-made questionnaire before and after using the application. Results The number of specialists in the both Delphi rounds was 15 and the mean work experiences were 17.6 years. The most important elements for asthma self-management were avoiding exposure to allergen and triggers (96%), drug treatment (94.6%), and how to use the therapeutic tools (92.4%), and the most important functionalities were alerting the patients when they did not control asthma (92%), setting reminders for timely drug use (85.4%) and therapeutic tools (82.6%), recording prescription drugs (82.6%), and peak flow meter values (82%). Usability evaluation showed that 30 patients with asthma, 8 IT specialists, and 2 physicians evaluated the application at a “good” level. The mean score of the patients' knowledge before intervention was 2.43 ± 0.95 which after intervention was significantly increased to 4.3 ± 0.56 (p < 0.001). Conclusion Considering the desirable outcomes of application evaluation and a positive impact of this educational intervention on asthma patients' knowledge, it is possible to use mobile-based self-management programs to help these patients to manage illness and gain knowledge and self-management skills.

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Economic Evaluation of Text-Messaging and Smartphone-Based Interventions to Improve Medication Adherence in Adolescents with Chronic Health Conditions: A Systematic Review

Cited by 106 publications

References 40 publications

eHealth and mHealth interventions in pediatric cancer: A systematic review of interventions across the cancer continuum

eHealth and mHealth interventions in pediatric cancer: A systematic review of interventions across the cancer continuum

Mobile phone interventions to improve adolescents' physical health: A systematic review and meta‐analysis

Enhancing Asthma Patients' Self-Management through Smartphone-Based Application: Design, Usability Evaluation, and Educational Intervention

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