Economic Impact of Lyme Disease

Zhang, Xinzhi; Meltzer, Martin I.; Peña, César; Hopkins, Annette; Wroth, Lane; Fix, Alan

doi:10.3201/eid1204.050602

Cited by 83 publications

(68 citation statements)

References 17 publications

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“…Our study confirms and extends results of the 1993 survey by Vanderhoof and Vanderhoof-Forschner, in which 19% of patients with Lyme disease reported that they had lost a job due to the illness [21], and is consistent with those of Zhang and colleagues, who found that loss of productivity -such as lost work time -constituted over half of the costs associated with late Lyme disease [28]. The economic burden for patients and society may be exacerbated as a result of several factors, including delayed diagnosis that permits an acute condition to become chronic, the inability to obtain medical insurance when Lyme disease is a pre-existing condition, and denial of disability benefits to patients who are unable to work.…”

Section: Burden Of Illnesssupporting

confidence: 91%

“…Although IDSA discounts the severity of Lyme disease symptoms, the utilization of hospital and emergency room services by respondents suggests a substantial burden of illness. This corroborates previous reports that patients with Lyme disease suffer a disability equal to that of congestive heart failure [25,35] and that hospital and emergency room services constitute a large component of direct medical costs in Lyme disease [28]. In addition, a quarter of survey respondents received disability benefits at some point in their illness, and over half of these respondents received disability for two years or more, indicating significantly compromised ability to function in their work capacities.…”

Section: Burden Of Illnesssupporting

confidence: 88%

“…Although patients with delayed diagnosis and treatment generally improve once treatment is instituted, delayed treatment is more difficult, less successful, and more costly [25][26][27][28]. In a cost-of-illness study published in 2006, Zhang and colleagues found that the mean annual cost of illness was $1310 per patient for early Lyme disease, but was $16,199 for late Lyme disease-roughly a 12-fold increase [28]. The travel burden for Lyme disease patients is quite high, with the majority of survey respondents traveling more than 50 miles and a substantial minority traveling more than 500 miles for Lyme disease treatment.…”

Section: Access To Healthcarementioning

confidence: 99%

See 2 more Smart Citations

Healthcare access and burden of care for patients with Lyme disease: A large United States survey

2011

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Section: Burden Of Illnesssupporting

confidence: 91%

Section: Burden Of Illnesssupporting

confidence: 88%

Section: Access To Healthcarementioning

confidence: 99%

See 1 more Smart Citation

Healthcare access and burden of care for patients with Lyme disease: A large United States survey

2011

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“…CRE infections are more costly than episodes of other infectious diseases. For example, in 2016 values, the cost of one influenza case is an estimated $2807 to $8889 to society [22]; the societal costs of pertussis in adolescents and adults is an estimated $600 to $1169 [23]; Lyme disease cost societyan estimated $451 per case [24]; and food-borne illness because of salmonella cost society $3899 per case [25]. CRE infections are also more costly compared with the annual costs of some chronic diseases.…”

Section: Discussionmentioning

confidence: 99%

Potential economic burden of carbapenem-resistant Enterobacteriaceae (CRE) in the United States

Bartsch

McKinnell

Mueller

et al. 2017

Clinical Microbiology and Infection

167

121

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Objectives The Centers for Disease Control and Prevention considers carbapenem-resistant Enterobacteriaceae (CRE) an urgent public health threat; however, its economic burden is unknown. Methods We developed a CRE clinical and economics outcomes model to determine the cost of CRE infection from the hospital, third-party payer, and societal, perspectives and to evaluate the health and economic burden of CRE to the USA. Results Depending on the infection type, the median cost of a single CRE infection can range from $22 484 to $66 031 for hospitals, $10 440 to $31 621 for third-party payers, and $37 778 to $83 512 for society. An infection incidence of 2.93 per 100 000 population in the USA (9418 infections) would cost hospitals $275 million (95% CR $217–334 million), third-party payers $147 million (95% CR $129–172 million), and society $553 million (95% CR $303–1593 million) with a 25% attributable mortality, and would result in the loss of 8841 (95% CR 5805–12 420) quality-adjusted life years. An incidence of 15 per 100 000 (48 213 infections) would cost hospitals $1.4 billion (95% CR $1.1–1.7 billion), third-party payers $0.8 billion (95% CR $0.6–0.8 billion), and society $2.8 billion (95% CR $1.6–8.2 billion), and result in the loss of 45 261 quality-adjusted life years. Conclusions The cost of CRE is higher than the annual cost of many chronic diseases and of many acute diseases. Costs rise proportionally with the incidence of CRE, increasing by 2.0 times, 3.4 times, and 5.1 times for incidence rates of 6, 10, and 15 per 100 000 persons.

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“…Lyme borreliosis has large socioeconomic consequences. Studies from different countries show that maximum estimated costs per patient approach e9000, including direct and indirect costs (Maes et al 1998, Meltzer et al 1999, Zhang et al 2006, Henningsson et al 2010, Morlando et al 2012.…”

Section: Introductionmentioning

confidence: 99%

High Risk of Tick Bites in Dutch Gardens

MulderSara

Vliet

BronWichertje

et al. 2013

Vector-Borne and Zoonotic Diseases

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Lyme borreliosis is the most prevalent tick-borne disease throughout the Northern Hemisphere. Because the disease has large socioeconomic consequences, there is an urgent need to further educate the public to stimulate preventive behavior. Unfortunately, risk factors for tick bites are poorly known. In this study, we determined the habitats and activities at risk for tick bites for people of different age categories using reports of Dutch citizens. Most people, 43%, were bitten in the forest, and an unexpected large number of people reported tick bites from their gardens (31%). Hiking, hobby gardening, and playing were the most-mentioned activities during which tick bites were received; people aged from 50 to 69 and children below 10 were bitten most. Different age categories were bitten in different habitats and during different activities. People aged from 0 to 60 reported most tick bites related to visiting a forest and hiking, whereas people older than 60 were mainly bitten in gardens. The percentage of garden and hobby gardening tick bites increased with age, but was also high for children less than 10 years of age. We suggest that these findings should be taken into account for the development of prevention strategies aiming to decrease the number of Lyme borreliosis cases.

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Economic Impact of Lyme Disease

Abstract: Since 1975, Lyme disease has become the most common vectorborne inflammatory disease in the United States.

Cited by 83 publications

References 17 publications

Healthcare access and burden of care for patients with Lyme disease: A large United States survey

Healthcare access and burden of care for patients with Lyme disease: A large United States survey

Potential economic burden of carbapenem-resistant Enterobacteriaceae (CRE) in the United States

High Risk of Tick Bites in Dutch Gardens

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