Economic impact of medication error: a systematic review

Walsh, Elaine; Hansen, Christina Raae; Sahm, Laura J.; Kearney, Patricia M.; Doherty, Edel; Bradley, Colin

doi:10.1002/pds.4188

Cited by 130 publications

(121 citation statements)

References 34 publications

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“…The cost of adverse drug reaction resembles and within range cost what reported by Marques, FB et al [15] The second high cost of patient suffered from drug-related problems was the medications errors that are related poor knowledge of medications errors and absent of patients medication educations program at most hospitals. The cost of medication resembles what reported by Walsh, EK et al [16] The third one was the patient need medications for such disease, but the patient not referred to hospitals for management that's lead to the disease switched from acute to chronic or complications maybe occurred. Some patient may take the medications with them self without any consultation and perhaps is appropriate for them lead to sequences and consumed of the cost.…”

Section: Discussionmentioning

confidence: 69%

Cost Analysis of Drug-related Problems in Saudi Arabia: Patients’ and Healthcare Providers’ Perspective

Alomi¹,

Al-Shaibani²,

Alfaisal³

et al. 2018

JPPCM

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Section: Discussionmentioning

confidence: 69%

Cost Analysis of Drug-related Problems in Saudi Arabia: Patients’ and Healthcare Providers’ Perspective

Alomi¹,

Al-Shaibani²,

Alfaisal³

et al. 2018

JPPCM

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“…The high IQR figures relative to the respective medians reflect the fact that the data include a small number of high value outliers. The mean total cost per claim of €151 916 is significantly higher than the €111 727 per claim (adjusted to euro 2015 figures) for 62 anaesthetic claims reported in the UK . This difference may be reflective of different litigation costs in the 2 jurisdictions.…”

Section: Discussionmentioning

confidence: 76%

“…The median (IQR) total cost of those medication-related claims which concluded with a payment to the plaintiff was €60 991 (€135 253), including median (IQR) damages of €33 858 (€45 388).The high IQR figures relative to the respective medians reflect the fact that the data include a small number of high value outliers. The mean total cost per claim of €151 916 is significantly higher than the €111 727 per claim (adjusted to euro 2015 figures) for 62 anaesthetic claims reported in the UK 10. This difference may be reflective of different litigation costs in the 2 jurisdictions.The total cost of the 48 claims analysed in this study amounted to almost €7.3 million.…”

mentioning

confidence: 75%

“…Avoidable ADRs cost the National Health Service (NHS) in England £98.5 million (€114.4 million approximately) annually, accounting for 181 626 bed‐days and causing and contributing to 712 and 1708 deaths respectively . A systematic review of the economic impact of ME found the cost per error, adjusted to euro 2015 values, ranged from €2.58 to €111 727 . Closed claims analysis has been employed to determine litigation costs associated with MEs.…”

Section: Introductionmentioning

confidence: 99%

“…5 A systematic review of the economic impact of ME found the cost per error, adjusted to euro 2015 values, ranged from €2.58 to €111 727. 10 Closed claims analysis has been employed to determine litigation costs associated with MEs. A study of litigation resulting from drug errors in anaesthesia in the NHS identified 93 claims with a total cost of £4.9 million (€5.7 million approximately).…”

mentioning

confidence: 99%

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Medication related litigation in Ireland: A 6‐year review

McCullagh¹,

Slattery

2019

Brit J Clinical Pharma

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Aims The primary aims of the study were to identify those medications most frequently associated with clinical litigation in Ireland and to quantify the cost of such litigation. Secondary aims were to identify where in the medication‐use process claims were most likely to arise, the medication incident types involved and the primary injury alleged. Methods The National Incident Management System (NIMS) for incident and claims management was searched to identify all medication‐related claims finalised from 2011 to 2016 (inclusive). The physical case files were obtained and additional data not available on NIMS was extracted in order to build a detailed picture of the incident and subsequent claim. Results The search identified 79 relevant claims, of which 48 closed with a payment to the plaintiff. These 48 claims involved 54 medications. Medication groups identified included general anaesthetics (n = 7), opioids (n = 6), penicillins, antithrombotics and local anaesthetics (all n = 5). The errors alleged occurred exclusively at the administration (58%) and prescribing (42%) stages of the medication‐use process. Medication incident types included wrong dose/strength (n = 17), wrong drug (n = 7) and adverse drug reaction (n = 6). The most commonly pleaded primary injuries were allergic reaction (n = 9), deterioration in clinical status (n = 9) and post‐traumatic stress disorder (n = 8). The median total cost of these claims was €60 991, including median damages of €33 858. Conclusions This study links data on medication incidents, actual harm to patients and litigation costs. Thus, it presents a comprehensive picture of the consequences of medication error.

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Reducing medication errors for adults in hospital settings

Ciapponi

Nievas

Seijo

et al. 2021

Cochrane Database of Systematic Reviews

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BackgroundMedication errors are preventable events that may cause or lead to inappropriate medication use or patient harm while the medication is in the control of the healthcare professional or patient. Medication errors in hospitalised adults may cause harm, additional costs, and even death. ObjectivesTo determine the e ectiveness of interventions to reduce medication errors in adults in hospital settings. Search methodsWe searched CENTRAL, MEDLINE, Embase, five other databases and two trials registers on 16 January 2020. Selection criteriaWe included randomised controlled trials (RCTs) and interrupted time series (ITS) studies investigating interventions aimed at reducing medication errors in hospitalised adults, compared with usual care or other interventions. Outcome measures included adverse drug events (ADEs), potential ADEs, preventable ADEs, medication errors, mortality, morbidity, length of stay, quality of life and identified/ solved discrepancies. We included any hospital setting, such as inpatient care units, outpatient care settings, and accident and emergency departments. Data collection and analysisWe followed the standard methodological procedures expected by Cochrane and the E ective Practice and Organisation of Care (EPOC) Group. Where necessary, we extracted and reanalysed ITS study data using piecewise linear regression, corrected for autocorrelation and seasonality, where possible.

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Economic impact of medication error: a systematic review

Cited by 130 publications

References 34 publications

Cost Analysis of Drug-related Problems in Saudi Arabia: Patients’ and Healthcare Providers’ Perspective

Cost Analysis of Drug-related Problems in Saudi Arabia: Patients’ and Healthcare Providers’ Perspective

Medication related litigation in Ireland: A 6‐year review

Reducing medication errors for adults in hospital settings

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