This study investigates the economics of suicide in South Africa using the Mortality and Causes of Death data from death notification as well as regional economic data for the 2006‐2008 period. Using an inflation rate that varies by month and across province of residence as a proxy for economic performance, the results indicate a negative relationship between inflation and suicide, suggesting that suicides are countercyclical. When controlling for month and province fixed effects, however, the inflation coefficient, albeit remaining negative, is no longer significant, except in the female sample. Suicide is more prevalent among younger individuals, while the greatest proportion of suicide is seen among men. Suicides also exhibit a strong seasonal variation, with peaks in spring and summer, with December having the highest suicide prevalence. The overall results indicate a negative but insignificant relationship between economic performance and suicide in South Africa, with socio‐economic differences and individual characteristics accounting for most of the variation in suicide.