We propose a set of novel non-macro-based uncertainty indicators that rely on the frequency of Google searches (NM-GSIs) for the following health-, environmental-, security-, and politicalrelated topics: "Symptom", "Pollution", "Terrorism", and "Election". By means of VAR investigations, we document that an intensification of people interest in non-macro-based topics harms the US real economic activity. In particular, NM-GSI shocks generate (i) a significant drop in consumer credit and (ii) a mild decrease (increase) in production (unemployment) levels. Noteworthy, rising non-macro-based uncertainty is found to have stronger influence on the outstanding level of consumer credit than rising macro-based uncertainty. Our findings suggest that increasing interest in specific non-macro-based topics might be associated with raising people's anxiety. A battery of robustness checks confirms our main findings.