“…Airlift bioreactors were suggested as the possible alternatives to stirred tank bioreactors because they exhibited relative high gas-liquid mass transfer, good liquid mixing, low liquid shear force as a result of no mechanical moving parts and low operating cost [19][20][21][22]. Airlift bioreactors are available in different configurations such as internal-loop column, external-loop column, cone-shape, cone-shape with baffle inside, and flatpanel, with the selection criteria depending on types of bioprocess, microorganisms, growth media, sterilization options, scaling up, ease of construction and operation, space limitation and budget [3,19,[23][24][25]. Unfortunately, only one report on DHA production in airlift bioreactor is available.…”