Ecotoxicological aspects of the use of parabens in the production of cosmetics

Abstract

Parabens are synthetic preservatives that are used on a large scale in the cosmetics, pharmaceutical and food industries. Their task is primarily to prolong the shelf life of selected products-cosmetics, medicines or food-by maintaining their microbiological purity. Parabens protect products against deterioration and microorganisms, extending their durability by up to several months without interfering with their composition and operation. Parabens do not change the aroma, taste, density or other characteristics of cosmetic or food products. However parabens, which occur in most cosmetics with a creamy or liquid formula (face creams, body lotions, foundation, tonics, lipsticks, deodorants, perfumes), are becoming increasingly worse because of the prolonged list of side effects that they may cause. The presence of intact paraben esters in human body tissues has now been confirmed by independent measurements in human urine, and the ability of parabens to penetrate human skin intact without breakdown by esterases and to be absorbed systemically has been demonstrated through not only in vitro studies but also in vivo investigation using healthy human subjects.

Pelatihan dan Pendampingan Produksi Minyak Atsiri Sereh Wangi untuk Penguatan Aroma Kosmetik di UMK Bali Sari Wangi Desa Sepang

“…Tujuan penambahan paraben adalah untuk mencegah tumbuhnya bakteri maupun jamur pada kosmetik. Namun, penggunaan paraben sering dikaitkan dengan permasalahan alergi, obesitas, dan infertilitas (Barabasz et al, 2019) Disamping itu, bahan pewangi atau fragrance akhir-akhir ini juga semakin massif ditambahkan pada produk kosmetik selain untuk meningkatkan aroma juga berperan untuk memposisikan produk diantara produk lainnya. Salah satu bahan pewangi sintetik yang sering digunakan pada produk kosmetik seperti shampoo, body lotion, sabun mandi, detergen adalah polyethylene terephthalate (Becker et al, 2014).…”

Ecological problems associated with personal care products and the role of microbes in aquatic environment

“…Subsequently, dioxygenase enzymes cleave the aromatic ring, initiating degradation and production of β-ketoadipate. Further reactions lead to the formation of acetyl-CoA and succinate, which participate in the TCA cycle to generate ATP (Barabasz et al, 2019) and alcohol. Esterases are the primary enzymes involved in this initial stage.…”

The Source of Parabens in Urban River Water: The Evidence From Outdoor Multimedia Environment in Six Metropolitan Cities, China

“…They were first used in medicine in 1920 and first discovered to have estrogenic activity in 1998 . In the decades that followed, studies have found that PBs can cause skin diseases , and affect the development of reproductive organs, − as well as lead to disorders of thyroid hormone levels, obesity, , premature birth, weight loss, and hyperactivity of newborns . The potential risk of exposure to PBs and its impact on human health has attracted increasing attention.…”