Ecthyma Gangrenosum

Funk, Etai; Ivan, Doina; Gillenwater, Ann M.

doi:10.1001/archoto.2009.93

Cited by 21 publications

(4 citation statements)

References 3 publications

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“…A weak mechanical defense barrier and underdeveloped cellular or humoral immunity increased the risk of infection in newborns [ 4 , 5 ]. In the general population lesions are usually present in the gluteal and perineal regions or on the extremities and trunk, but rarely are they found on the face or neck [ 6 ], whereas, in most reported cases of preterm EG, the face is affected as was the case in our patient [ 7 , 8 ]. Even though literature has shown that most children with EG had either previously undetected immunodeficiencies or transient risk factors such as immunosuppressive therapy that predisposed them to the development of the disease, not many newborn cases have been reported [ 9 ].…”

Section: Discussionmentioning

confidence: 72%

An Extraordinary Cause of the Sucking Difficulty: Ecthyma Gangrenosum

Ceylan

Demir

Kocaman

et al. 2016

Case Reports in Medicine

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Ecthyma gangrenosum is a cutaneous lesion often associated with pseudomonas aeruginosa bacteremia, even though it may develop without bacteremia and may originate from other bacterial and fungal organisms. Pseudomonas aeruginosa bacteremia or sepsis, which mainly affects immunocompromised patients, frequently occurs in hospitals. This lesion typically occurs on the extremities and gluteal and perineal regions. In this report we present a case of ecthyma gangrenosum in a premature newborn occurring secondary to pseudomonas sepsis causing sucking dysfunction due to tissue loss in the lip, soft palate, and tongue.

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Section: Discussionmentioning

confidence: 72%

An Extraordinary Cause of the Sucking Difficulty: Ecthyma Gangrenosum

Ceylan

Demir

Kocaman

et al. 2016

Case Reports in Medicine

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“…In the second nonbacteremic form, the lesions occur at the site of direct inoculation into the skin. Pseudomonas aeruginosa produces protease, elastase, phospholipase C, and exotoxin A that are responsible for the direct tissue and vessel destruction leading to ulcerative lesions [5,8,9] . Mesenchymal Stem Cells (MSCs) are one type of stem cells that can differentiate into a variety of tissue-specific cell types.…”

Section: Discussionmentioning

confidence: 99%

A case report: Secretome of Wharton’s jelly-derived MSCS (SWJ-MSCS) for treatment of Echtyma Gangrenosum

Pratiwi¹,

Chandra²,

Tan³

2021

Int. J. Dermatol. Venereology Leprosy Sci.

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Polythene is the most common plastic. The annual global production is around 80 million tones. It's Ecthyma gangrenosum (EG) is an uncommon skin infection caused most commonly by Pseudomonas aeruginosa. It is characterized by a macule that rapidly changes into a gangrenous ulcer with a black eschar surrounded by erythema. We report a case of EG in a previously healthy woman treated with intracutaneous injection and topical gel of Wharton's Jelly-derived MSCs (SWj-MSCs) secretome that showed a significant result in the wound healing process, and the patient was satisfied with the results.

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“…It was first described in association with Pseudomonas septicemia by Barker in 1897 and was later given the name “ecthyma gangrenosum” by Hitschmann and Kreibich. [ 1 ] It is usually seen in critically ill patients with neutropenia or underlying immune deficiency who present with skin lesions that begin as an erythematous, nodular or hemorrhagic vesicles that turn into necrotic ulcers with eschar formation. [ 2 ] The skin lesions are usually widespread over the area involved.…”

Section: Introductionmentioning

confidence: 99%

Ecthyma gangrenosum in the periorbital region in a previously healthy immunocompetent woman without bacteremia

Sarkar¹,

Patra²,

Mondal³

2016

Indian Dermatol Online J

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Ecthyma gangrenosum (EG) is a cutaneous lesion classically associated with potentially fatal Pseudomonas septicemia in immunocompromised patients. Other bacterial and fungal pathogens have also been implicated. Although EG typically occurs in immunocompromised or neutropenic patients, it may occasionally affect a previously healthy person. The cutaneous findings are characteristic with small indurated papulovesicles progressing rapidly to necrotic ulcers with surrounding erythema and a central black Eschar. While lesions can occur at any site, most are commonly found over the buttocks, perineum, limbs, and axillae. We describe a case of EG in periorbital region in a previously healthy woman who responded to appropriate antibiotic treatment for Pseudomonas. It is very important to establish the diagnosis early so that appropriate systemic antibiotic therapy can be initiated to reduce morbidity and potential mortality.

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Ecthyma Gangrenosum

Cited by 21 publications

References 3 publications

An Extraordinary Cause of the Sucking Difficulty: Ecthyma Gangrenosum

An Extraordinary Cause of the Sucking Difficulty: Ecthyma Gangrenosum

A case report: Secretome of Wharton’s jelly-derived MSCS (SWJ-MSCS) for treatment of Echtyma Gangrenosum

Ecthyma gangrenosum in the periorbital region in a previously healthy immunocompetent woman without bacteremia

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