Ectopic breast cancer: Two case reports and review of the Japanese literature

Kawahara, Futoshi; Noguchi, Masakuni; Yamamichi, Noboru; Konishi, Fumio; Yagasaki, Ryo; Minami, Masaki; Earashi, Mitsuharu; Kinoshita, Kazuo; Taniya, Takao; Miyazaki, Itsuo

doi:10.1007/bf02967055

Cited by 12 publications

(5 citation statements)

References 9 publications

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“…[ 29 ] 2 2: WE + RT 2: Recurrence free (3 years) Kawahara et al. [ 30 ] 59 31–84 37 IDC + 3 MC + 1 ApC + 2 Muci C + 1 MC IS 26: WE+LND 26: R Mastect 2: WE 5: Nod. Recurrence 54: Recurrence free (1 month to 13 years) Haddad et al.…”

Section: Discussionmentioning

confidence: 99%

Primary ectopic axillary breast cancer: a case series

et al. 2021

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Introduction Ectopic breast tissue is present in 2–6% of women. Ectopic breast cancer represents an uncommon disease accounting for about 0.3% of all breast neoplasms, limiting the available evidence. Thus, we aim to report long-term outcomes in five cases treated at our institution. Case series Our Tunisian patients’ median age was 48 years (33–60 years), and the median follow-up was 8 years (4–10 years). The ectopic breast tissue was located four times in the right axilla. The median tumor size was 25 mm (15–55 mm). Four of the patients underwent a wide local excision and axillary lymph node dissection. Three of those women had positive lymph nodes; thus, they received adjuvant chemotherapy, radiation therapy, and hormone therapy. The patient with a negative lymph node (case 5) had adjuvant radiation therapy and hormonal therapy. One of the patients (case 1) had a positive supraclavicular lymph node and received radiation therapy, chemotherapy, and hormonal therapy. The latter developed a locoregional relapse after 4 years and was treated with mastectomy and chemotherapy. One patient (case 4) had a distant metastasis after 2 years of follow-up and received chemotherapy. The three other patients were free of relapse during their follow-up period. Conclusion Primary axillary breast carcinoma is a rare entity. Despite the paucity of literature, our findings and authors’ recommendations suggest that local excision can be performed safely with promising outcomes in this subset of patients.

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Section: Discussionmentioning

confidence: 99%

Primary ectopic axillary breast cancer: a case series

et al. 2021

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“…Although ectopic breast cancer can make patients more vulnerable to second primary breast cancer, this risk is not strong enough to perform ipsilateral mastectomy for prophylaxis [4]. The prognosis of ectopic breast cancer depends on nodal metastasis, as is the case with typical breast cancer [14].…”

Section: Discussionmentioning

confidence: 99%

Unexpected presentation of accessory breast cancer presenting as a subcutaneous mass at costal ridge: a case report

Thasanabanchong

Vongsaisuwon

2020

J Med Case Reports

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Background: During embryogenesis, bilateral thickening of ectoderm from anterior axillary folds to inguinal folds, called mammary ridges or milk lines, develops into breast tissues. Only a pair in the pectoral area is spared from regression and continuously develops into normal breasts. Accessory breasts can result if the regression process is incomplete. These ectopic breasts can change physiologically and pathologically similar to normal breasts. Unsurprisingly, they are capable of turning malignant. Reported cases show the most common area for accessory breast cancer to be the axillary area. We report a rare case of accessory breast cancer over the costal ridge. Case presentation: We present the case of a 51-year-old Asian woman who complained of an enlarged mass lower to her left breast developed over the period of 3 months while on contraceptive pills. Unaware that the mass could be an accessory breast, the primary doctor had prescribed oral contraceptives. After our patient had noticed that the mass was obviously growing, she decided to consult a surgeon as the mass continued to grow. Expected to be benign, the mass was investigated by ultrasonography and then excised surgically. A pathology report identified the mass to be a carcinoma of the ectopic breast tissue. However, sentinel lymph node biopsy showed no nodal metastasis of all four lymph nodes. Following surgery, she received chemotherapy, radiation, and antihormonal treatment. After 2 years of postoperative follow up, she remained free of disease. Conclusions: This patient was diagnosed as having accessory breast cancer which presented with a subcutaneous mass. As this condition is exceptionally rare but curable by early treatments, we recommend surgeons to consider potential malignancy when patients present with a subcutaneous mass.

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“…Accessory mammary tissue is reported to occur in 2 to 6% in women 3–5 . Ectopic mammary tissue is usually located in the axilla and less frequently in the vulva, 6,7 but it can be found in any point from the axilla to the groin 8 and is frequently bilateral 9 …”

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confidence: 99%