Ectopic Cushing Syndrome: A Rare Cause of Electrolyte Derangements

Fanous, Nada; Schwartz, Cody; Gargus, Nathan; Casella, Julio Leey

doi:10.1016/j.amjmed.2019.08.047

Cited by 3 publications

(2 citation statements)

References 5 publications

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“…20 Table 2 describes the presentations and management strategies of the most common endocrine paraneoplastic syndromes. 19,[21][22][23][24][25][26][27][28][29][30][31][32] Humoral paraneoplastic syndromes result when an immune response occurs to tumor antigens that also yields autoantibodies against normal cellular components to trigger corresponding autoimmune syndromes. Autoimmune paraneoplasias are altogether rare, affecting <1% of patients with cancer, and most commonly present as neurologic, rheumatologic, and dermatologic syndromes.…”

Section: Paraneoplastic Syndromesmentioning

confidence: 99%

“…Carcinoid syndrome only occurs when monoamines are injected into the systemic circulation, either directly through the pulmonary circulation or from hepatic or retroperitoneal metastases of the bowel lesions 20 . Table 2 describes the presentations and management strategies of the most common endocrine paraneoplastic syndromes 19,21‐32 …”

Section: Paraneoplastic Syndromesmentioning

confidence: 99%

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Oncologic emergencies and urgencies: A comprehensive review

Rothberg

Quest

Yeung

et al. 2022

CA A Cancer J Clinicians

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Patients with advanced cancer generate 4 million visits annually to emergency departments (EDs) and other dedicated, high‐acuity oncology urgent care centers. Because of both the increasing complexity of systemic treatments overall and the higher rates of active therapy in the geriatric population, many patients experiencing acute decompensations are frail and acutely ill. This article comprehensively reviews the spectrum of oncologic emergencies and urgencies typically encountered in acute care settings. Presentation, underlying etiology, and up‐to‐date clinical pathways are discussed. Criteria for either a safe discharge to home or a transition of care to the inpatient oncology hospitalist team are emphasized. This review extends beyond familiar conditions such as febrile neutropenia, hypercalcemia, tumor lysis syndrome, malignant spinal cord compression, mechanical bowel obstruction, and breakthrough pain crises to include a broader spectrum of topics encompassing the syndrome of inappropriate antidiuretic hormone secretion, venous thromboembolism and malignant effusions, as well as chemotherapy‐induced mucositis, cardiomyopathy, nausea, vomiting, and diarrhea. Emergent and urgent complications associated with targeted therapeutics, including small molecules, naked and drug‐conjugated monoclonal antibodies, as well as immune checkpoint inhibitors and chimeric antigen receptor T‐cells, are summarized. Finally, strategies for facilitating same‐day direct admission to hospice from the ED are discussed. This article not only can serve as a point‐of‐care reference for the ED physician but also can assist outpatient oncologists as well as inpatient hospitalists in coordinating care around the ED visit.

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