Ectopic Pregnancy and Assisted Reproductive Technologies: A Systematic Review

Velalopoulou, Anastasia; Peschos, Dimitrios; Ospan, Mynbaev; Eliseeva, Marina; Verginadis, Ioannis I.; Simos, Yannis V.; Tsirkas, Panagiotis; Karkabounas, Spyridon; Kalfakakou, Vasiliki; Evangelou, Angelos; Kosmas, Ioannis

doi:10.5772/20842

Cited by 3 publications

(5 citation statements)

References 125 publications

(106 reference statements)

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“…Although the prevalence of HPs with multiple embryos is rising due to widespread application of ARTs [1], spontaneously occurred HPs are remaining very rare. Therefore this unique case is represent the scientifically and practically significance to be analyzed in detail.…”

Section: Discussionmentioning

confidence: 99%

“…There are also other risk factors of EP development, including sexually transmitted and pelvic inflammatory diseases (PIDs), specially adnexitis and salpingitis with formation of hydrosalpings, intraperitoneal and periadnexal adhesions and partial occlusion of Fallopian Tubes (FTs), as well as gynaecological surgical procedures, which may lead to tubal dysfunction and ectopic embryo implantation [1]. Moreover an increased prevalence of multiple pregnancies during conception after stimulated ovulation is multiplying risk of Heterotopic Pregnancy (HP), when ectopic and intrauterine pregnancies are simultaneously coexisted.…”

Section: Introductionmentioning

confidence: 99%

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Case Report of Combined Twin Tubal and Intrauterine Pregnancies

Mynbaev¹

2012

J Clin Case Rep

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Case of heterotopic quadruplet pregnancy with coexistence of tubal and intrauterine twins.twins and its successful surgical management with brief literature review. Design:A case report supplemented with brief literature review and discussion.Setting: City clinical university hospital. Patient (s):Heterotopic quadruplet pregnancy with tubal and intrauterine twins in a 31-year-old woman after natural conception. Intervention (s):Laparoscopy, adhesiolisys, aspiration of tubal embryos through tubotomy and cervical dilatation and vacuum aspiration of intrauterine embryos as well as vaginal and intraoperative laparoscopic ultrasound examination.Main outcome measure (s): Physical examination, laparoscopy and postsurgical hCG serum assay, as well as preintra-and postoperative vaginal ultrasound and intraoperative laparoscopic sonography. Result (s):Successful diagnosis and treatment of a case of heterotopic quadruplet pregnancy with coexistence of tubal and intrauterine twins in a 31-year-old woman with 6 artificial abortions, pelvic inflammatory diseases and periadnexal adhesions, after natural conception was described. An intraoperative laparoscopic sonography was applied to complete diagnosis of heterotopic pregnancy with coexistence of tubal and intrauterine twins after control of bleeding and stabilization of patient condition due to necessity to perform an emergency surgery. The case was supplemented with a brief review of literature and discussion. Conclusion (s):A unique case of heterotopic quadruplet pregnancy with coexistence of tubal and intrauterine twins after natural conception was presented in the first time.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Case Report of Combined Twin Tubal and Intrauterine Pregnancies

Mynbaev¹

2012

J Clin Case Rep

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“…Ectopic Pregnancies after IVF specially for tubal disease account for approximately 8-10% of pregnancies (7,48). Hysteroscopic SEED minimizes the chances of "losing" the embryo, and virtually eliminates ectopic pregnancies (tubal, placenta previa, cervical, or heterotopic) from embryo transfer, as the embryo(s) is embedded into the endometrium and not floating in the uterus.…”

Section: Discussionmentioning

confidence: 99%

“…From a clinical practice perspective in our new age of pre-implantation diagnosis and screening, the embryo transfer process may now be regarded as a rate limiting factor. Various techniques for embryo transfer (ET) have been advocated to increase pregnancy rates while reducing side effects from the procedure, such as lost embryos and ectopic pregnancies (5)(6)(7)48). In addition, the advantages of using different catheters have been debated (8)(9)(10)(11).…”

Section: Introductionmentioning

confidence: 99%

SubEndometrial Embryo Delivery (SEED) with Egg Donation – Mechanical Embryo Implantation

Kamrava¹,

Yin²

2012

Enhancing Success of Assisted Reproduction

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“…Ovarian(0.5%) and 3.Abdominal[1%]:-primary (rare) and secondary which can be intraperitoneal [common] or extraperitoneal [broad ligament]. Factors [3] delaying or preventing migration of fertilized ovum to the uterine cavity like PID/salpingitis [4], contraception failure: IUCD [more with progesterone IUCD], Sterilisation operation, Tubal surgeries, Intrapelvic adhesions following pelvic surgery, artificial 5 reproductive techniques (ART) like GIFT, IVF, Previous ectopic [10-15%], Prior induced abortion ,increasing age , Developmental defects in tube increase the risk of ectopic pregnancy. Similarly factors facilitating nidation in tube like 1.Early resumption of trophoblastic activity and 2.Tubal endometriosis also promote ectopic pregnancy.…”

Section: Introductionmentioning

confidence: 99%

Ectopic Pregnancy, Still A Life Threatening Emergency - A Clinical Study Of 100 Cases

Kavitha

Geetha

et al. 2014

Asian J. Health. Sci.

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Ectopic pregnancy is still a major challenge & its incidence is on the rise due to changes in lifestyle & advances in medical practice. The objective was to study incidence, clinical presentation, risk factors & management of cases that presented in our hospital over a four -year period. A Prospective study of 100 cases presenting as ectopic pregnancy from 15-1-2010 to 15-1-2014.During this period total of 3176 deliveries & 1347 gynaecological surgeries were recorded. 100 patients had ectopic gestations accounting for 3.1% of all deliveries & 7.4% of gynaecological surgeries. Peak age group was 20-29y in 59cases(59%). Gestational age at presentation was 6-8weeks for most of the cases (62%). 59 cases (59%) were multiparous & 41(41%) were nulliparous. All had symptoms suggestive of ectopic pregnancy (amenorrhea, abdominal pain, giddiness, bleeding pervaginum). Diagnosis was confirmed by urine pregnancy test & USG. Common risk factors present were previous surgery ie LSCS-30(30%), Tubectomy-19(19%); Abortions-32(32%); Infertility-36(36%); PID-16(16%).Out of 100cases, 93 (93%) were ruptured & 7(7%) unruptured. Unruptured cases were treated medically using Methotrexate. Laparotomy was done for ruptured cases. Commonest site of Ectopic was ampulla (60%). Salpingectomy was done for most cases (73%).Although case-fatality has decreased, ruptured Ectopic gestation continues to be a common life-threatening emergency making tubal conservation inapplicable. This is of concern in a society with high premium on child-bearing.

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Ectopic Pregnancy and Assisted Reproductive Technologies: A Systematic Review

Cited by 3 publications

References 125 publications

Case Report of Combined Twin Tubal and Intrauterine Pregnancies

Case Report of Combined Twin Tubal and Intrauterine Pregnancies

SubEndometrial Embryo Delivery (SEED) with Egg Donation – Mechanical Embryo Implantation

Ectopic Pregnancy, Still A Life Threatening Emergency - A Clinical Study Of 100 Cases

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