Ectopic Prostatic Tissue in the Uterine Cervix

Larraza-Hernandez, Oscar; Molberg, Kyle; Lindberg, Guy; Albores‐Saavedra, Jorge

doi:10.1097/00004347-199707000-00018

Cited by 37 publications

(14 citation statements)

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“…However, there are reported examples in the uterine cervix and vagina. 4,5,8,9,15 McCluggage and Young reported glands with positivity for both prostate-specific antigen (PSA) and prostatic acid phosphatase (PrAP) in a distinct vaginal lesion, the tubulosquamous polyp. 7 In this article, we present morphologically and histogenetically variable lesions occurring in the lower female genital tract with features of prostatic differentiation.…”

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confidence: 99%

Prostatic-type Tissue in the Lower Female Genital Tract: A Morphologic Spectrum, Including Vaginal Tubulosquamous Polyp, Adenomyomatous Hyperplasia of Paraurethral Skene Glands (Female Prostate), and Ectopic Lesion in the Vulva

Kazakov¹,

Stewart

Kacerovská³

et al. 2010

American Journal of Surgical Pathology

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The investigators report a series of prostatic-type lesions occurring in the lower female genital tract. The cases included a 4.5-cm mass representing hyperplasia of the glandular and stromal tissue of paraurethral Skene gland, a small ectopic prostatic lesion in the vulva, and 4 tubulosquamous vaginal polyps. All lesions were immunopositive for prostate-specific antigen and/or prostatic acid phosphatase. A brief discussion of the earlier published material is included.

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confidence: 99%

Prostatic-type Tissue in the Lower Female Genital Tract: A Morphologic Spectrum, Including Vaginal Tubulosquamous Polyp, Adenomyomatous Hyperplasia of Paraurethral Skene Glands (Female Prostate), and Ectopic Lesion in the Vulva

Kazakov¹,

Stewart

Kacerovská³

et al. 2010

American Journal of Surgical Pathology

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“…In the cervix, it can take the form of a tumor-like mass (25,26). In the ovary, it usually has been associated with a mature cystic teratoma (27), but in one, the origin seemed to have been from mesonephric rests (28).…”

Section: Discussionmentioning

confidence: 99%

Skene's Gland Adenocarcinoma Resembling Prostatic Adenocarcinoma

Pongtippan

Malpica

Levenback

et al. 2004

International Journal of Gynecological Pathology

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An 88-year-old woman presented with gross hematuria and a 3-cm periurethral mass. Biopsy revealed an adenocarcinoma resembling prostatic adenocarcinoma; the tumor cells were positive for keratin and prostate-specific antigen. The serum level of prostate-specific antigen was elevated; the carcinoembryonic antigen and CA-125 serum levels were normal. One year after external beam radiotherapy, the patient is without evidence of disease. This is the sixth case of a urethral prostatic-type adenocarcinoma, tumors that are most likely of Skene's gland origin.

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“…[32][33][34] Five of these cases were incidental findings in women from 22 to 38 years of age, and 1 presented as a cervical mass in a 77-year-old woman. 33 Histologically, there is a circumscribed proliferation of ducts and acini in the superficial cervical stroma, many of which display papillary and cribriform patterns.…”

Section: Ectopic Prostatic Tissuementioning

confidence: 99%

“…33 Though rare, ectopic prostatic tissue may be underreported, as 5 additional cases have been reported since the first case report in 1997. 32 Understandably it is not usually considered when examining the cervix, and what is not looked for will most likely be missed. In the differential diagnosis, a benign mimic is the LEGH, as described above.…”

Section: Ectopic Prostatic Tissuementioning

confidence: 99%

Nonneoplastic Glandular Lesions of the Cervix

Yeh

2006

Pathology Case Reviews

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A diverse number of nonneoplastic glandular lesions of the cervix may mimic well-differentiated invasive adenocarcinoma (minimal deviation adenocarcinoma). It is essential for the practicing pathologist to be familiar with the histopathologic spectrum of these lesions to avoid the pitfalls of misinterpretation and inappropriate management of a benign condition. Careful morphologic examination of routinely stained sections is the cornerstone of diagnosis; however, there are cases with atypical features posing a diagnostic challenge where ancillary techniques such as immunohistochemical stains may be of value. This review presents a case of tunnel clusters that illustrate the importance of recognizing benign morphologic features and includes a discussion of other pseudoneoplastic glandular lesions of the uterine cervix commonly encountered in practice.

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Ectopic Prostatic Tissue in the Uterine Cervix

Cited by 37 publications

References 0 publications

Prostatic-type Tissue in the Lower Female Genital Tract: A Morphologic Spectrum, Including Vaginal Tubulosquamous Polyp, Adenomyomatous Hyperplasia of Paraurethral Skene Glands (Female Prostate), and Ectopic Lesion in the Vulva

Prostatic-type Tissue in the Lower Female Genital Tract: A Morphologic Spectrum, Including Vaginal Tubulosquamous Polyp, Adenomyomatous Hyperplasia of Paraurethral Skene Glands (Female Prostate), and Ectopic Lesion in the Vulva

Skene's Gland Adenocarcinoma Resembling Prostatic Adenocarcinoma

Nonneoplastic Glandular Lesions of the Cervix

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