Ectopic Prostatic Tissue in Urethra: A Clinicopathological Entity and a Significant Cause of Hematuria

Polyps of the Prostatic Urethra

“…Adenomatous polyp with prostatic type epithelium has many synonyms [ 1,2,5,6,11,15,16], since the etiology of this lesion is still controversial [3,6,11,15,17], The prostatic nature of this lesion has been demonstrated by the immunoperoxidase staining [2,5,15,18] and ultrastructural study [6], Since microscopic findings in our patients were consistent with those of typical adenoma tous polyp [1,2], we did not perform such evaluations. Baroudy and O'Connell [12] reported that papillary ade noma of the prostatic urethra was the most common cause of hematospermia and hematuria in young men in Saudi Arabia.…”

“…They include adeno matous polyp with prostatic type epithelium [1,5], adeno matoid polyp [2,7], polypoid urethritis [1,8], fibrous polyp [1,9], transitional cell papilloma and inverted pap illoma [ 10], Although these lesions are heterogeneous, any type of polyps arising from the prostatic urethra can be a cause of hematuria [5,6,11,12], hematospermia [6,[11][12][13] or dysuria [5,14], In this series we experienced two types of these lesions, one was adenomatous polyp with prostatic type epithelium and the other was polypoid ure thritis.…”

“…To our knowledge, only one case has been reported [20], Walker et al [2] described a case of adeno matous transformation in their series and emphasized the potential for malignant transformation. Recurrent devel opment after the local resection is unusual [6], but several cases have been reported [ 1,18].…”

“…They are histologically heterogeneous lesions. Clinically, gross or microscopic painless hematuria is the common est symptom [2], Hematospermia and dysuria are less fre quent symptoms in these conditions [6], We review our experiences obtained in 4 patients with the prostatic urethral polyps, 3 of whom showed adeno matous polyps and 1 demonstrated polypoid urethritis. The clinical and histological features of these lesions are described below.…”

Benign Polyp with Prostatic-Type Epithelium in the Anterior Urethra Accompanied with Urethral Stricture

“…To date, there have been increasing reports of benign polyp with prostatic-type epithelium [1] or ectopic pros tatic tissue [2], The major involved site is the prostatic urethra [3,4], and some cases occurring in the urinary bladder [5,6] and in the anterior urethral [1,[7][8][9][10][11][12][13][14] have been reported. As to the pathogenesis of this lesion, sev eral hypotheses or explanations have been postulated and yet it is controversial.…”