Ectopic thyroid in the gallbladder accompanied with gallbladder adenoma

Li, Yanxu; Li, Shijun; Wang, Meng; Tong, Ling

doi:10.1097/md.0000000000018293

Cited by 7 publications

(5 citation statements)

References 15 publications

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“…A comprehensive database search identified a total of 10 reported cases related to ectopic thyroid in the hepatoduodenal ligament and its surrounding areas from 1991 to 2022 (8)(9)(10)(11)(12)(13)(14)(15)(16)(17). The case information is summarized in Table 1.…”

Section: Discussionmentioning

confidence: 99%

Ectopic thyroid in the hepatoduodenal ligament: a case report and literature review

Zhang,

Cui,

Wang

et al. 2024

Front. Oncol.

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Ectopic thyroid arises from abnormal development of thyroid primordial tissues as it migrates to the lower interstitium during the embryonic period, which can occur at various locations during the descent process. However, ectopic thyroid in the subdiaphragmatic area is extremely rare. In this case, we report a case of ectopic thyroid located in the hepatoduodenal ligament. The 60-year-old female patient was admitted to hospital with gallbladder stones and cholecystitis. Preoperative imaging showed a mass in the hepatoduodenal ligament. As the patient declined a needle biopsy of the mass, the nature of the mass remained unclear prior to surgery. The patient subsequently underwent laparoscopic cholecystectomy and exploratory resection of the mass. The histopathology of the resected mass showed the characteristics of ectopic thyroid, and immunohistochemical staining revealed positive expression of thyroid transcription factor-1 and thyroglobulin. The diagnosis of ectopic thyroid was established. Upon confirming the diagnosis, comprehensive neck examination revealed the presence of a normally functioning thyroid gland. Throughout the four-year follow-up period, the patient’s thyroid ultrasonography and thyroid function tests indicated no abnormalities. Ectopic thyroid in the hepatoduodenal ligament and surrounding areas is an extremely rare clinical abnormality, achieving a clear diagnosis before initiating treatment offers diagnostic and treatment insights and clues for clinicians when differentiating masses within this region.

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Section: Discussionmentioning

confidence: 99%

Ectopic thyroid in the hepatoduodenal ligament: a case report and literature review

Zhang,

Cui,

Wang

et al. 2024

Front. Oncol.

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“…found in the lungs, breast, heart, thymus, etc (15-18). The digestive system was found in stomach, gallbladder, hepatic hilum, pancreas, etc (19)(20)(21). Urinary and reproductive systems are seen in adrenal glands, ovaries, fallopian tubes, uterus, etc (22,23).…”

Section: Discussionmentioning

confidence: 99%

The clinicopathological features, treatment outcomes and follow-up results of 47 ectopic thyroid gland cases: a single-center retrospective study

Gao,

He,

et al. 2023

Front. Endocrinol.

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BackgroundEctopic thyroid gland (ETG) is an uncommon clinical condition, presenting various challenges and limitations in its regulate diagnosis and treatment currently. This study aims to enhance our understanding of ETG and improve the strategies for its diagnosis and treatment.MethodsThe retrospective single-center study was conducted, encompassing clinical data from ETG patients screened at our institution between 2013 and 2022. Patients were categorized based on the location of the disease, and follow-ups were performed on each.ResultsThis study included a total of 47 patients who were confirmed to hav confirmed to have ETG. Among them, we found 29 cases of accessory thyroid and 18 cases of aberrant thyroid. Furthermore, 42 cases exhibited the single ETG, while 5 cases displayed the double ETG. The distribution of the ETG was as follows: 20 were lingual, 10 were submandibular, 10 were lateral cervical, 4 were thoracic mediastinal, 1 was esophageal, and 7 were ovarian. Of these cases, 22 patients underwent surgery, 18 received thyroid hormone replacement therapy, and 7 were placed under observation. All patients were followed up for 59.4 (12-117) months. No significant abnormalities were detected at the conclusion of the follow-up period.ConclusionETG is frequently observed in the head and neck, particularly in lingual. Accessory thyroid glands are commonly reported, with most cases being single ETG. Notably, these glands usually do not manifest specific clinical symptoms. Therefore, the appropriate and comprehensive examinations during the initial diagnosis are crucial to avoid misdiagnosis. Treatment should be individualized, and long-term follow-up is essential for managing ETG effectively.

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“…Ectopic thyroid tissue is a rare clinical condition with a prevalence of 1/100,000 to 300,000 individuals in the general population, and the incidence is much lower in men than in women [1]. Usually, aberrant ectopic thyroid tissue occurs along the midline and rarely in the gall bladder, lung, adrenal gland, heart or liver [2][3][4][5][6]. To our knowledge, most ectopic thyroid tissue in the lung is in a single lobe or homolateral lobes, and only 4 cases of ectopic intrapulmonary thyroid tissue in the bilateral lung lobes have been reported in the literature [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Rare ectopic thyroid tissue as multiple bilateral pulmonary nodules: a case report and literature review

Tan

Kuang

et al. 2022

J Cardiothorac Surg

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Background The prevalence of ectopic thyroid tissue is 1 in every 100,000 to 300,000 persons in the general population, and ectopic thyroid tissue in the bilateral lung lobes is even rarer. Due to its rarity, there is no definitive or standard guidance on the diagnosis and treatment of ectopic thyroid tissue presenting as multiple bilateral pulmonary nodules. Case presentation A 56-year-old woman presented with multiple bilateral pulmonary nodules, and the patient had a history of hyperthyroidism but had no symptoms of ectopic thyroid tissue. Computed tomography (CT) demonstrated multiple solid nodules in both lungs, and the largest nodule (sized 15 × 14 mm) was located in segment 5 of the upper left lung. The initial diagnosis based on imaging was metastatic malignancies. Positron emission tomography-computed tomography (PET-CT) showed multiple bilateral intrapulmonary nodules that had slightly increased metabolism (SUVmax 1.7). The largest pulmonary nodule and another nodule in the left lung were resected by video-assisted thoracoscopy surgery (VATS). The pathological and immunohistochemical (IHC) examinations confirmed a diagnosis of ectopic thyroid tissue. No postoperative adjuvant therapy was given, and the patient was discharged 3 days after the operation and had regular follow-up examinations. Conclusion The diagnosis of ectopic thyroid tissue in the bilateral lung lobes is extremely difficult and should be considered carefully. PET-CT and surgical resection of intrapulmonary nodules are alternatives for clinicians in diagnosing ectopic thyroid tissue. Regular postoperative follow-up is needed.

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Ectopic thyroid in the gallbladder accompanied with gallbladder adenoma

Cited by 7 publications

References 15 publications

Ectopic thyroid in the hepatoduodenal ligament: a case report and literature review

Ectopic thyroid in the hepatoduodenal ligament: a case report and literature review

The clinicopathological features, treatment outcomes and follow-up results of 47 ectopic thyroid gland cases: a single-center retrospective study

Rare ectopic thyroid tissue as multiple bilateral pulmonary nodules: a case report and literature review

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