Eczema in pregnancy

Weatherhead, Sophie; Robson, Stephen C.; Reynolds, Nick J.

doi:10.1136/bmj.39227.671227.ae

Cited by 50 publications

(35 citation statements)

References 34 publications

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“…According to previous studies, approximately 25% of females who have AD experience improvement during pregnancy, and more than 50% of the AD female patients experience deterioration during pregnancy 7,8 . Moreover, female patients with AD often show a deterioration of cutaneous symptoms in relation to the menstrual cycle 9 .…”

Section: Introductionmentioning

confidence: 99%

The Influence of Pregnancy and Menstruation on the Deterioration of Atopic Dermatitis Symptoms

Cho

Kim

et al. 2010

Ann Dermatol

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Background: Female patients with atopic dermatitis (AD) often experience cutaneous deterioration associated with their pregnancy or menstrual cycle. Objective: We wanted to determine the prevalence of symptom aggravation as related to pregnancy and the menstrual cycle in female patients with AD. Methods: One hundred female patients with AD were included in the study and interviews were performed. The total IgE level and the Eczema Area and Severity Index score of the patients were retrospectively reviewed. Results: Ninety seven patients replied the questionnaire, and among them, 23 patients had completed at least 1 pregnancy. Among the 23 women who experienced pregnancy, 14 (61%) had noticed deterioration of their clinical symptoms during pregnancy. Of the 97 females, 31 (32%) patients had noticed deterioration of their AD as related to their menstrual cycle. For the patients who were sub-grouped as the intrinsic type of AD, the prevalence of symptom aggravation as related to pregnancy was significantly higher as compared to that of the extrinsic type of AD patients (p=0.048). Conclusion: Of the 97 patients, 45 (46%) females answered that they have experienced deterioration of AD during pregnancy or in relation to their menstrual cycle, and this suggests the relation of a hormonal influence on the clinical manifestations of AD. (Ann Dermatol 22(2) 180∼185, 2010)

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Section: Introductionmentioning

confidence: 99%

The Influence of Pregnancy and Menstruation on the Deterioration of Atopic Dermatitis Symptoms

Cho

Kim

et al. 2010

Ann Dermatol

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“…In our personal experience, a majority of patients present with worsening of their eczema during pregnancy, some get better, and some show no change. This is in line with some smaller studies [2,3]. Looking into changes in severity of atopic eczema, it has to be considered that a lot of women reduce treatment by the time they get pregnant or even when they are planning to get pregnant.…”

Section: Atopic Eczemamentioning

confidence: 58%

Atopic Eczema and Itch in Pregnancy: Therapeutic Considerations

Schnopp

Ring

2012

Curr Derm Rep

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With an estimated prevalence of 3 % in adults, atopic eczema is probably the most common cause for itch in pregnancy. Differential diagnoses of an itchy skin condition in a pregnant patient have to be considered carefully, because specific treatment is important to minimize risks for the mother and the child. Treatment is challenging, because safety data are limited for many drugs currently used to treat inflammatory dermatoses, such as topical steroids, calcineurin inhibitors, antihistamines, and systemic steroids in pregnancy. On the other hand, undertreatment of severely affected patients may lead to complications, such as superinfection.

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“…However, if the sunlight occurs concomitantly with high heat or humidity, thereby triggering sweating and possibly pruritus, it may exacerbate the disease . AD that has not responded satisfactorily to topical steroids can be managed with the addition of ultraviolet (UV) phototherapy . The best results have been achieved with UV light A (UVA)1 (340–400 nm), broadband UV (UVA + UVB 290–400 nm) and narrow band UVB (311 nm) .…”

Section: Safementioning

confidence: 99%

Treatment of atopic dermatitis in pregnancy

Babalola

Strober

2013

Dermatol Ther

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Atopic dermatitis (AD), also referred to as eczema, is one of the most frequently observed skin diseases in pregnant patients. The presentation and histopathology of this condition during pregnancy is identical to that of the non-pregnant individual. AD is a T-helper 2 dominant disease and may worsen during pregnancy, which favors this population of T-lymphocytes. AD management during pregnancy requires special precautions to avoid harming the fetus. Herein is an exploration of the different options available for the treatment of the pregnant patient with AD. The management of concomitant bacterial and viral infections is also discussed.

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Eczema in pregnancy

Abstract: Many women with eczema experience flares during pregnancy, and management must take account of the possible effects of some treatments on the fetus

Cited by 50 publications

References 34 publications

The Influence of Pregnancy and Menstruation on the Deterioration of Atopic Dermatitis Symptoms

The Influence of Pregnancy and Menstruation on the Deterioration of Atopic Dermatitis Symptoms

Atopic Eczema and Itch in Pregnancy: Therapeutic Considerations

Treatment of atopic dermatitis in pregnancy

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