Edema agudo hemorrágico da infância: relato de três casos

Abstract

Acute Hemorrhagic Edema of Infancy is an infrequent leukocytoclastic vasculitis which occurs almost exclusively in children between 4 months and 2 years of age. It is clinically characterized by the triad fever, purpuric lesions on the face, auricular pinna and extremities, and edema. Although the cutaneous findings are dramatic and of rapid onset, the prognosis is favorable, with spontaneous resolution within 1 to 3 weeks. Three cases are described in which clinical and histopathological findings are characteristic of acute hemorrhagic edema of infancy. Keywords: Edema; Purpura, Schoenlein-Henoch; Vasculitis Resumo: O Edema Agudo Hemorrágico da Infância é uma vasculite leucocitoclástica pouco frequente, que ocorre, quase exclusivamente, em crianças entre 4 meses e 2 anos de idade. Caracteriza-se, clinicamente, pela tríade febre, lesões purpúricas em face, pavilhões auriculares e extremidades e edema. Embora os achados cutâneos sejam dramáticos e de surgimento rápido, o prognóstico é favorável, com resolução espontâ-nea dentro de 1 a 3 semanas. Descrevem-se três casos cujos achados clínicos e histopatológicos são característicos de edema agudo hemorrágico da infância.

Acute Hemorrhagic Edema of Infancy: an unusual diagnosis for the general pediatrician

“… 3 , 5 , 13 Immunofluorescence testing can reveal C3, fibrinogen and IgM deposits and, less commonly, IgM, IgE or IgA, the latter a common finding in HSP. 16 , 17 …”

Acute hemorrhagic edema of infancy: a rare case report from Syria

“…Although the etiology of the disease is not clearly understood at this time, some reports in the literature suggest some potential explanations, such as the existence of an infection that occurred previously and contributed to the development of the disease in more than 75% of cases (urinary infection – upper respiratory infection – otitis media – pneumonia) 6 . Other contributing factors include using specific medications and antipyretics, such as paracetamol, and getting particular vaccinations, such as the triple vaccine (DPT – diphtheria, pertussis, and tetanus) 7 . Clinical and histological criteria are used to make a diagnosis.…”