1945
DOI: 10.1001/archneurpsyc.1945.02300040008002
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Edema and Trophic Disturbances of the Lower Extremities Complicating Prefrontal Lobotomy

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1948
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Cited by 18 publications
(1 citation statement)
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“…(Le Gros Clark and Meyer, 1950;Wall, Glees, and Fulton, 1951;Cowan and Powell, 1956;Nauta, 1961;Powell, Cowan, and Raisman, 1963, and it may be that a tractotomy confined to certain of these pathways is significant in producing the effects observed. Vertical incisions in this area, however, produce serious autonomic and trophic disturbances (Knight, 1943;Meyer and Beck, 1954;Ziegler and Osgood, 1945;Beck, McLardy, and Meyer, 1950), which are attributable to associated damage to the striatum (Meyer and McLardy, 1948) indicating that the substantia should not be approached from above and that in a stereotactic operation a strictly localized lesion should be formed in the substantia innominata by a destructive agent which could not produce marginal effects by infarction or haemorrhage in the region of the striatum. Although electrocoagulation or ultrasonic methods might prove to be satisfactory when the site and size of the optimum lesion had been finally determined, we decided for research purposes to use seeds of radioactive Ytrrium Y90 whose short range of emanation would ensure a strictly localized effect.…”
mentioning
confidence: 99%
“…(Le Gros Clark and Meyer, 1950;Wall, Glees, and Fulton, 1951;Cowan and Powell, 1956;Nauta, 1961;Powell, Cowan, and Raisman, 1963, and it may be that a tractotomy confined to certain of these pathways is significant in producing the effects observed. Vertical incisions in this area, however, produce serious autonomic and trophic disturbances (Knight, 1943;Meyer and Beck, 1954;Ziegler and Osgood, 1945;Beck, McLardy, and Meyer, 1950), which are attributable to associated damage to the striatum (Meyer and McLardy, 1948) indicating that the substantia should not be approached from above and that in a stereotactic operation a strictly localized lesion should be formed in the substantia innominata by a destructive agent which could not produce marginal effects by infarction or haemorrhage in the region of the striatum. Although electrocoagulation or ultrasonic methods might prove to be satisfactory when the site and size of the optimum lesion had been finally determined, we decided for research purposes to use seeds of radioactive Ytrrium Y90 whose short range of emanation would ensure a strictly localized effect.…”
mentioning
confidence: 99%